Opal gene skin care

Opal gene skin care DEFAULT

Opal Kratom Review

Kratom aficionados praise it for its ability to stimulate the body, provide a significant energy boost and bring relief from a range of health conditions. Bienvenue sur le site internet de la Circonscription premier degré de Bresse. A Comprehensive Guide To Maeng Da Kratom. OPAL had hoped to renovate the house in order to provide a permanently affordable home for a family in need. us/stemtalk/episode-6. Aug 13, 2021 · Thanks for reading our best kratom products review to see which are the top vendors and brands who offer pure, high quality kratom supplements. AI chipset, which uses smart technology to automatically adapt to a coil's resistance and set the power output at an appropriate voltage. Required Cookies & Technologies. Lovingly made energy bracelet from natural minerals such as aventurine, carnelian and yellow opal, which support the body's health at all levels. There are many uses including: Under the tongue; mixed with food and drink; as a massage oil. has been created to facilitate needs of small and midlle size compagnies that want to invest or sell their products or se QSICL. Beautiful double layer black and white dot stack pendant ,encased in uv light reactive luna from north star glass. At about 15% Indica, ans 85% Sativa it is clearly mislabeled as an Indca strain. Kratom review on Green Hulu from soapkorner. 0 0 Reviews. -Super White Jongkong - POTENT AF!!!!! Certainly upper-mid. A Review of Psychosocial Risk Factors Among Transgender Patients Seeking Bariatric Surgery, Leah Hecht, Chazlyn Miller, Lisa R. So, if you want to take a moderate dosage you’ll only need to take 4 to 5 capsules. Kratom is banned: Alabama, Arkansas, Indiana, Rhode Island, Tennessee, Vermont,. 99 Green Maeng Da - $27. 2 Subscription Mystery Boxes: $49 + 100% free shipping. Most vendors use 00 sized capsules which only hold. At low doses, kratom acts as a stimulant, making users feel more energetic. Kratom is also sold as a treatment for panic attacks. Zach, 87 of Buford passed away August 18, 2021. Mr Nice Guys carries a wide variety of kratom products such as kratom pills, capsules, and powder. Meet White Maeng Da kratom Review: stimulant, energy booster, mood elevator, pain reliever, and more besides, White Maeng Da may be just the ticket to help you deal with the strains of modern life. indo is the longest lasting variety this gerbil has had, not to say there aren't longer lasting varieties out there. You may have heard that kratom comes from Thailand, but did you know that kratom can be found all over Southeast Asia? Learn more about kratom today at Kratora! [email protected] This was one of my favorites last year? And I thought it was all gone! So happy to find it. The only ALL GLASS Smoke Shop in Houston. rcforevery Ethiopian Hydrophane Opal they offer online is a SCAM!!! Sent. A sativa and a Sativa Dominant Hybrid. Kraken Kratom. As we’ve seen, Maeng Da kratom is a potent remedy. A trusted supplier of quality mitragyna speciosa products since 2014, Kraken has created and implemented the highest standards in the kratom industry. We prioritize people over profits. Be the first to review “Opal Kratom. Kratom trees and similar varieties contain what are known as mitragynine and 7-hydroxymitragynine. May 01, 2021 · 2021年05月01日国际域名到期删除名单查询,2021-05-01到期的国际域名,包括. For example, anyone who has never consumed Kratom before should start from as little as 1. GIOK BURMA TYPE A bkn pirus red borneo teratai opal kecubung dareh. Opal Kratom 30Ct Capsules (SELECT PIC FOR MORE OPTIONS) Log in to see product price. Green Malay Green Maeng Da. , its affiliates or divisions (including without limitation TForce Freight), which are not affiliated with United Parcel Service, Inc. Browse Categories. Add to Wishlist. So weird cuz it's so subtle, yet so perfect. Required Cookies & Technologies. The liquid form is often marketed as a treatment for muscle pain, or to suppress appetite and stop cramps and diarrhea. About two hours before he took it he downed about 16 ounces of grapefruit juice to potentiate the kratom. has been created to facilitate needs of small and midlle size compagnies that want to invest or sell their products or se QSICL. ⇒ Visit the Official Website of White Maeng Da Kratom for the best discount. In comparison to different Kratom strains such as Bali, Malay, this strain has less side effects like nausea as well as wobbles. Category: Kratom. Apr 08, 2019 · Kratom is a tropical tree native to Southeast Asia, with leaves that can have psychotropic effects. It doesn't bind to opioid receptors, and its results differ from these of pharmaceutical opioids. Welcome to Headspace gifts and glass, Buffalo's Highest end smoke shop. Kraken Kratom is named after the huge, iconic sea monster and is a well-known option for purchasing regular Kratom. Anyways it's an amazing get shit done strain. Larch Ave, STE 3 Elmhurst IL, 60126 United States ( 331) 979-7113; [email protected] Recovering from an addiction is a life-long commitment; it takes long-term dedication and maintenance. Anyone in Alabama should stop by or check out this smoke shop online or give them. Maeng Da is an extremely potent, strong blend of Kratom. An assistor takes the information, assigns the EIN, and provides the number to an authorized individual over the. Mystic Island Kratom Product Line. indo is the longest lasting variety this gerbil has had, not to say there aren't longer lasting varieties out there. In Short, No. Although it is quite rare, many Kratom users recommend Kratom Red Hulu as a must-try due to its high and well-balanced alkaloid profile. Price $399. American Green Smoke (AGS) is the most siginificant worldwide distribution of premium Glass, vape, E-liquid, CBD and Kratom. Maverick's mother or acute-on-chronic downcast with the extract used daily for pain relief. Frogsong Farm Drops Plus is our strongest Organic Olive Oil based tincture. This kratom vendor seems pretty run-of-the-mill but has excellent prices. The volume of the two primary alkaloids found in Kratom, 7-hydroxymitragynine and mitragynine, is larger than in some other varieties of Kratom. About Zippo Lighters The Zippo name, the brand, the look and feel is famous - and rightly so - throughout the entire world. Carlin, and Kellie Martens. Updated: August 7th, 2021 When it comes to popular kratom strains, another type of kratom that has a fan base is Vietnam. This premium kratom blend is ideal for people looking to improve the most essential aspects of their daily routine by promoting overall balance and well-being. REMARKABLE HERBS. due to the relativly low price of their kratom. Bracelet length: 16 cm, 18 cm, 20 cm. ~Qingdao Sunshine International Trade Co,. Falsifying your age for the purpose of purchasing products from this web site is illegal and punishable by law. Green Kratom CBD Gummies are indeed the most efficient and helpful CBD product. local time, Monday through Friday. For regular Kratom users, any dose between 2. RAPPER KUSH. There are 2 additional side effects that I have observed with Kratom which is similar to what I have experienced with opioids. 2012; 8(1):15–32. Our Premium Maeng Da Capsules are made with a specially crafted blend formulated to give users a comprehensive kratom experience. This mixed with Wild Harvest Green PMD is my new go-to for work. Red Maeng Da delivers the best of Kratom's alkaloids along with a synergy of calm and balance. 99 strain Bali - $27. Top brands, low prices & free shipping on many items. 21 thg 1, 2020 - the pars nervosa reported. April 9, 2021 June 2, 2021. Kratom is the name of a tree from the coffee family native to Southeast Asia. 投稿者: suehiro. Maverick's mother or acute-on-chronic downcast with the extract used daily for pain relief. PA Botanicals Offers Variety Of Kratom Packs And Sample Packs. 135 reviews of Kavasutra "Sure to be a neighborhood institution! I've had Kava and Kratom may times before but until now there wasn't a place to be served fresh! The bar fits perfectly into the healthy options on East 10th and I'd rather relax and drink kava in this chill atmosphere than be crammed like sardines into a hectic alcohol bar. Zach, 87 of Buford passed away August 18, 2021. This bill aimed to introduce regulations that would ensure that vendors who sell or plan to sell kratom products: would register with the Idaho. This mixed with Wild Harvest Green PMD is my new go-to for work. Locally owned and operated in Buffalo since 2010. Beautiful double layer black and white dot stack pendant ,encased in uv light reactive luna from north star glass. CBD PHARM DELTA 8 DISPOSABLE DEVICE - 18CT Login for Pricing. Opal Kratom Add to wishlist. Exclusive Kratom Extract Dsiplay of 12ct Extract is a concentrated form of Mitragyna Speciosa that contains a full spectrum of alkaloid derived from the whole leaf-11%. Anecdotal reviews recommend that some heavy kratom users undergo from what's generally known as post-acute withdrawal syndrome. Opal Kratom. 2012; 8(1):15–32. Your good capability and kindness in dealing with all things was helpful. The carefully carved wood, and silver and gold accents on this piece make it a perfect combination of bad-ass and beautiful. " The Indo Kratom is the only strain which can match the dual-benefits of Maeng Da. Our Carolina's Best CBD Infused Wellness and Skin Care Collection features CBD infused Massage Oil, Lip Balm, Body Lotion, After Shave, Beard Butter, Muscle Rub, Muscle Lotion, Facial Scrub, Herbal Skin Balm, Hand and Foot Butter, Facial Lotions, Acne Cream, Facial Serum and Anti-Aging Night Cream. For information on submitting an obituary, please contact The Herald-Dispatch by phone at 304-526-2793 or email at [email protected] Kratom is the name of a tree from the coffee family native to Southeast Asia. At about 15% Indica, ans 85% Sativa it is clearly mislabeled as an Indca strain. Apr 08, 2018 · there are many ways to recover pictures from corrupted sd card, but most important is to find the efficient and easy-to-use one. Advanced Search. Kratom, genus Mitragyna Speciosa, is an indigenous evergreen tree to Thailand and regionally throughout Southeast Asia, the plant is at times found in northern parts of Asia as well. VIVA XTREME. As an unregulated substance, Super Indo kratom's appropriate dosage cannot be properly codified. We are one stop wholesaler for the products of industry's top suppliers from vape hardware to glass and much more. Welcome to All Vape Stores, a global vape shop directory. 0 is considered as a moderate dose. cc等后缀域名,不含国际中文域名。. Seattle, 98104. McCurdy's statement on Kratom strains. Most people take kratom as a pill or capsule. 実際ルロイは、良人が妻を愛するようにサミイを愛して、第三者には滑新品,人気セール【ガット張り上げ済み】2019年秋発売モデル 。【応援クーポン10%OFF対象商品:10月20日まで】プリンス prince テニスラケット ジュニア ビースト 26 BEAST 26 7TJ104. Sovereignty 50x5 Stemline - Minor Accent Product Details: 18mm Horned Slide. However, this Kratom has been modified to become a great strain that it is today. Our Premium Maeng Da Capsules are made with a specially crafted blend formulated to give users a comprehensive kratom experience. 33 y/o from U. And as Kratom Crazy's reviews point out, they have extremely low prices that are hard to beat! Kraken Kratom. Oct 16, 2019 · The FDA has issued a strong warning against kratom use. Justice design recognizes that lighting is a necessity—that's. kratom krates reviews vcd is one s approach, kratom does clear shatter combines differentia- tion with coupon Get Code STAFF PICK Code. In fact, Maeng Da users. Enjoy shipping from, Fed Ex, UPS and USPS on Kratom USA. Welcome to Headspace gifts and glass, Buffalo's Highest end smoke shop. Add to Wishlist. The VooPoo Vinci Pod Device is a sophisticated vaping device that features. medicine man phoenix red vein bali 150ct 75gm capsules. 99 while 150 grams sells for. For information on submitting an obituary, please contact The Herald-Dispatch by phone at 304-526-2793 or email at [email protected] Organic Hippie is a Smoke Shop / Head Shop in Montgomery, Alabama. The white vein Kratom is used to boost your well-being, promoting better alertness. The Opal Peak Pro features a pearlescent metal band, helix inner-cone with an opal presented at the crown, and a clear base for a clean look. If you're a fan of a particular type of Bali kratom powder, capsules, or extract, then odds are that that same strain will be the perfect choice for you to brew a delicious kratom tea. If you're sick and tired of feeling… well, sick and tired, you'll be pleased to know there might a solution at hand. PURE LEAF KRATOM. Kratom, a popular herb of Southeast Asian origin, is prohibited for human consumption in Denver and has been the subject of numerous health warnings from the federal Food and Drug Administration. Quick View $ 450. The retailer has been around for several years, with mentions of the brand on Reddit dating back to at least 2018. VOOPOO Vinci Pod Device 40W Kit (now with Limited Edition Options) This sophisticated pod device features the GENE. Its leaves are dried and used to. Traditionally, in Southeast Asia, people have chewed its leaves or made them into a tea that’s used to fight fatigue and improve work productivity. Day Pipe by Hamilton Design. Opal kratom review. Even though Red Hulu Kratom powder is quite hard to. 21 reviews. Bogor MUNIMART. The Best Kratom!! This yellow strain is the best yelllow I have ever had. Red Hulu Kratom is one of the most powerful and unique Kratom strains available in the market. Glass Quick View. of and to in a is that for on ##AT##-##AT## with The are be I this as it we by have not you which will from ( at ) or has an can our European was all : also " - 's your We. A trusted supplier of quality mitragyna speciosa products since 2014, Kraken has created and implemented the highest standards in the kratom industry. It also gives a relaxing feeling while being gently. Quick View $ 450. Each Mitragyna Speciosa capsule. If you’re a fan of a particular type of Bali kratom powder, capsules, or extract, then odds are that that same strain will be the perfect choice for you to brew a delicious kratom tea. The answer might surprise you. Mar 25, 2011 · Continue Reading. Martin Mark, March 4, 2020 10 min read. McCurdy's statement on Kratom strains. " These words leave a bad taste in my mouth, especially when they refer to something that's supposed to be all-natural. The refillable pod system, made from medical grade materials, gives you the ability to choose your flavors. Log in with your email address, Facebook, or Google. Some people chew kratom leaves or brew the dried or powdered leaves as a tea. He is survived by his wife of 51 Bernard L. Vietnam kratom is an amazing strain that has a long list of effects and benefits. Have you. April 9, 2021 June 2, 2021. 11日〜15日まで夏休みをいただきます. Opal kratom review May 24, 2019 · Kratom is widely used in Southeast Asia as a recreational drug, and increasingly appears as a pure compound or a component of ‘herbal high’ preparations in the Western world. At this dose, all effects of green Hulu Kapuas show up. Locally owned and operated in Buffalo since 2010. Silver is expertly woven between each stone making them belong. paraben-free, sulfate-free, phthalate-free, appropriate for all skin types, non-irritating, sustainably sourced, plant-based ingredients, never tested on animals, made with hemp derived oil. Premium Kratom Maeng Da Capsules. We take great care to manually verify each vape shop listing to bring you only legitimate and reputable vape shops. kratom krates reviews vcd is one s approach, kratom does clear shatter combines differentia- tion with coupon Get Code STAFF PICK Code. The bottom line If you're thinking about taking kratom for depression or anxiety, take some. Martin Mark, February 11, 2020 11 min read. 24/08/2021. CBD PHARM DELTA 8 DISPOSABLE DEVICE - 18CT Login for Pricing. We will send you notification when it is back!. Basically, it's essentially impossible to actually overdose on the powdered leaf. That is designed to enhance general health and fitness in those who are suffering from stress, sadness, anxiety, mental discomfort, chronic problems, and so on. Our raw powders, leaf, and encapsulated products test at an average of >1. This premium kratom blend is ideal for people looking to improve the most essential aspects of their daily routine by promoting overall balance and well-being. This list will be continuously updated as new. 投稿日時: 2021年8月8日. This mixed with Wild Harvest Green PMD is my new go-to for work. At Cheap Tobacco we offer tobacco, CBD and vape products for the cheapest prices in town! Our multiple locations throughout Ohio allow us to be the cheapest and most convenient way for our customers to meet their tobacco needs. Brand: Purkratom. It features six different stones, all with their own healing ability. You have no items in your shopping cart. Required fields are marked *. いつもありがとうございます. As we’ve seen, Maeng Da kratom is a potent remedy. Silver is expertly woven between each stone making them belong. Category: Kratom. The top is crowned with a raw Zambian emerald, a faceted peridot and a stunning Ethiopian opal. Maeng da means "pimp grade" in Thai and the rumors are that this strain was made. VIVA XTREME. Reviews There are no reviews yet. Also known as mitragyna speciosa, it is grown in Thailand, Malaysia, and Indonesia. Check out Super Speciosa if you’re interested in kratom with lots of variety. BUY KRATOM POWDER AND CAPSULES ONLINE. I love all of the strains and use them all at different times of the day. Many kratom lovers can get confused about this term and don’t know exactly what to expect from it. Subscribe to our newsletter. But as with everything kratom, you have to understand the nuances. In this article, we will do a detailed OPMS kratom review and also share our candid opinion on the OPMS kratom products in the end. It's now been 90 days, and I still have not received my money back. This product has no stock!! Please enter your information to form bellow. As an unregulated substance, Super Indo kratom's appropriate dosage cannot be properly codified. They sell a kilo for only $69, which makes them one of the most affordable Kratom vendors available. home/power key for more than seven seconds. The hours of operation are 7:00 a. Martin Mark, March 4, 2020 10 min read. Red Maeng Da Kratom Capsules - 56g (2ozs). Another distinguishing feature of this white opal is the fact that it does not have any dark spots. The volume of the two primary alkaloids found in Kratom, 7-hydroxymitragynine and mitragynine, is larger than in some other varieties of Kratom. We prioritize people over profits. 2012; 8(1):15–32. The leaves contain a variety of alkaloids, 2 of which are primarily responsible for the plant's opiate like effects, mitragynine and 7-hydroxymitragynine. It is the conventional powder form of Kratom that is created by crushing the leaves of the Mitragyna Speciosa plant. Availability: In stock. Green Indo Kratom Review. We source our kratom from a vast network of reputable sources. We are one stop wholesaler for the products of industry's top suppliers from vape hardware to glass and much more. Kratom, also known as Mitragyna speciosa, is a tropical evergreen tree in the coffee family native to Southeast Asia. For example, anyone who has never consumed Kratom before should start from as little as 1. Home Decorators Collection Hd 1264 I 4 Light Antique Bronze Pendant W Vintage Bulbs Amazon Com from m. Premium Kratom Maeng Da Capsules. Kratom is the name of a tree from the coffee family native to Southeast Asia. Kratom Powder and Capsules are grouped separately. Red maeng da is one of many strains from the plant Kratom. Taxpayers can obtain an EIN immediately by calling the Business & Specialty Tax Line at (800) 829-4933. Quick View. Zach, 87, Buford. Red Borneo Kratom – Usage – Effects – Dosage – Vs Red Bali. Check out Super Speciosa if you’re interested in kratom with lots of variety. From all of us here at GBK, thank you for choosing us as your Kratom retailer. Many people find Kratom helps them with energy, pain, relaxation and motivation. Opal kratom review. User submitted reviews for kratom vendors and strains. Join a global community of travelers and local hosts on Airbnb. Sep 05, 2021 · Apps start from the home screen to explore apps and more. An analgesic is a chemical that relieves pain within the body. Services will be announced later. Including the ever popular Maeng Da, Bali, Borneo, Thai, Sumatra, and extracts like Ultra Enhanced Indo and Golden Reserve. it has become a. Bienvenue sur le site internet de la Circonscription premier degré de Bresse. Opal Kratom. which type kratom opioid maeng da bali A PBS Great American Read Top 100 Pick With extraordinary relevance and renewed recognition, George Orwell's 1984 takes on new life on this version. Martin Mark, March 4, 2020 10 min read. Green Malay Green Maeng Da. Browse Categories. Price $399. Kratom Powder and Capsules are grouped separately. Beautiful double layer black and white dot stack pendant ,encased in uv light reactive luna from north star glass. They sell a kilo for only $69, which makes them one of the most affordable Kratom vendors available. Traditionally, workers would chew on the leaves. Quick view. Required Cookies & Technologies. com Top Quality Organic Kratom World best strains 100% pure 0. Since most long-term customers will develop a bodily dependence on kratom, they may go through withdrawal signs when quitting. Martin Mark, March 10, 2020 9 min read. New York & Company Store Reviews: What To Know. Reviews and ratings for Kratom. ZERO was created to give you the perfect flavorful, simple, and low-cost alternative to smoking. Although it is quite rare, many Kratom users recommend Kratom Red Hulu as a must-try due to its high and well-balanced alkaloid profile. Come visit Cheap Tobacco where your tobacco is always cheap!. Historically, Kratom is native to Southeast Asia, Indonesia, Malaysia, and Thailand. Call WhiteSands Treatment today at (877) 855 3470 to learn more about the Alumni Program and how to join. White Maeng Da is arguably one of the most unique subvarieties of the classic Maeng Da kratom strain. Most Maeng da kratom capsules are dosed at 0. Reviews There are no reviews yet. whole herbs malay green vein 8oz 225gm powder (0 customer reviews) 0 sold $ 26. Its leaves are dried and used to. Trainwreck Kratom Powder will put you in a colorful mood. rcforevery Ethiopian Hydrophane Opal they offer online is a SCAM!!!. It had semi-opaque, buildable pigmentation with a smooth, more firmly-pressed consistency that was firm without being stiff to work with, though you'll want to use a moderately dense or denser brush. Virtually any strain of kratom is a great option for brewing a premium cup of kratom tea, including green, white, or red Bali kratom. April 9, 2021 June 2, 2021. They carry most of the popular kratom strains. This article covers a comprehensive […]. 99 Green Malay - $27. Dec 19, 2018 · A 2017 review concluded that the potential side effects of using kratom may outweigh the benefits. Address: 1002 Prince Edward St. Category: Kratom. Jun 5, 2011 #4. Top Kratom Strains You may not have heard of Kratom before which is why you know so little about it, on the other hand, you might have heard of it but be unfamiliar with its many strains. Glass Quick View. This strain of kratom comes from the island of Borneo in Indonesia. Basically, it's essentially impossible to actually overdose on the powdered leaf. Mr Nice Guys carries a wide variety of kratom products such as kratom pills, capsules, and powder. Including the ever popular Maeng Da, Bali, Borneo, Thai, Sumatra, and extracts like Ultra Enhanced Indo and Golden Reserve. 99 strain Bali - $27. Obituaries for The Herald-Dispatch must be received by. Kraken Kratom is named after the huge, iconic sea monster and is a well-known option for purchasing regular Kratom. Dec 13, 2017 · A recently published scientific review led by URMC associate professor of Psychiatry Marc Swogger, Ph. com Opal has a very tranquil glow that is pleasing in appearance. Anyone in Alabama should stop by or check out this smoke shop online or give them. An assistor takes the information, assigns the EIN, and provides the number to an authorized individual over the. Sovereignty 50x5 Stemline - Minor Accent Product Details: 18mm Horned Slide. Another distinguishing feature of this white opal is the fact that it does not have any dark spots. Martin Mark, March 10, 2020 9 min read. Quick View $ 450. Red Maeng Da Kratom Capsules - 56g (2ozs). By entering this website, you agree that you are 21 years of age or older. 107 People found this comment helpful. However, one question is asked by many who are seeking an alternative treatment …. topqualitykratom. The Red Maeng Da Kratom strain has become the most popular strain. Mar 25, 2011 · Continue Reading. 99 White Borneo - $27. Our five-pack is packaged in a 100% reusable or recyclable eco-friendly tin, with a reusable Boveda pack to ensure freshness for a very long time. At Cheap Tobacco we offer tobacco, CBD and vape products for the cheapest prices in town! Our multiple locations throughout Ohio allow us to be the cheapest and most convenient way for our customers to meet their tobacco needs. Kratom (Mitragyna speciosa) is a tree in the coffee family, found in Thailand and other tropical countries. Red Maeng Da Kratom Capsules - 28g (1oz) $21. 99 Green Malay - $27. it has become a. Anyways stumbled across some opal indo ssv from TFH. Aug 13, 2021 · Thanks for reading our best kratom products review to see which are the top vendors and brands who offer pure, high quality kratom supplements. topqualitykratom. But they also include many more herbal and natural-based products that deal with various health conditions. Jul 1, 1982 to 1983 · Starting QB Football · Hickory, North Carolina. This is a CBD may increase over of Sales and Operations and Kratom 3 Books adequate amount of the Guaran Seed Extracts standardized Jun 14 2020 Caffeine and 450mg as well as the from Caffeine Underground's perspective, from ginger, as this makes the Who Maeng Da Kratom is Organic Supplements Steve's Goods CBD Oil is excellent Week. Dec 13, 2017 · A recently published scientific review led by URMC associate professor of Psychiatry Marc Swogger, Ph. We are the Bentley of Head Shops and Yoga Studios. We prioritize people over profits. Since most long-term customers will develop a bodily dependence on kratom, they may go through withdrawal signs when quitting. Super Speciosa – Largest Kratom Variety. Don't mix with another batch cause you'll be waisting it since it essentially overpowers whatever you pair it with. Aug 27, 2021 · Apotheca is a plant medicine dispensary offering hand-selected CBD, H**p, Delta 8, Kratom, & other effective herbal remedies. Use our Soothe CBD infused Muscle Lotion in conjunction with a warm or cool pack to aid in absorption and rescue tired, achy, sore muscles, and joints. Opal Kratom Powder 1kg. White Maeng Da Green Maeng Da. CBD PHARM DELTA 8 DISPOSABLE DEVICE - 18CT Login for Pricing. Opal Kratom Green Borneo 15cap. Phytoextractum Is Truly A One-Stop Kratom Shop – A Review. PURE LEAF KRATOM. Visitors search for diamonds atop a 37 1/2-acre. Although this condition most commonly affects all the. Herbaldom Review (Green Hulu Kapuas) I've ordered two strains from Herbaldom, and I want to take this chance to say some nice things about the company and review the strains. Terry's nails are entirely white with a red or brownish band at the tip. Mystic Island Kratom Product Line. About two hours before he took it he downed about 16 ounces of grapefruit juice to potentiate the kratom. OPAL had hoped to renovate the house in order to provide a permanently affordable home for a family in need. The bottom line If you're thinking about taking kratom for depression or anxiety, take some. 投稿者: suehiro. Smoke shop as the name suggests is a shop that offers all kinds of cigarettes and accessories related to it to smoke lovers. OG is a Sativa-Dominant Hybrid. ( 19 customer reviews) $ 60. Aug 27, 2021 · Apotheca is a plant medicine dispensary offering hand-selected CBD, H**p, Delta 8, Kratom, & other effective herbal remedies. Red Borneo Kratom – Usage – Effects – Dosage – Vs Red Bali. Availability: In stock. Side Effects of Super Green Indo Kratom. Kratom is used by many Americans to relieve pain, combat fatigue, and even decrease opiate dependence. They do offer a variety of specialty strains, but we recommend using this resource for your basic Kratom needs. Our raw powders, leaf, and encapsulated products test at an average of >1. Opal kratom review. A head shop is a specialty store that sells a variety of tobacco-related paraphernalia. A trusted supplier of quality mitragyna speciosa products since 2014, Kraken has created and implemented the highest standards in the kratom industry. PURE LEAF KRATOM. There are 2 additional side effects that I have observed with Kratom which is similar to what I have experienced with opioids. Category: Kratom. When it's time to buy Kratom at inexpensive prices, Mystic Island is one of your best bets. Lovingly made energy bracelet made of natural minerals such as rosewood, yellow opal and cracked crystal, which support the health of the body at all levels. Be the first to review "Opal Kratom" Cancel reply. Sean Thomas Johnston p1 $ 350. Description Reviews (0) Description. RAPPER KUSH. Red Maeng Da Kratom Capsules - 28g (1oz) $21. Puffco Peak Pro Opal Edition. I felt sad when I discovered from your blog that such a natural remedy to people's pain is being bad at will in certain countries and regions without a thorough research on the. If you’re a fan of a particular type of Bali kratom powder, capsules, or extract, then odds are that that same strain will be the perfect choice for you to brew a delicious kratom tea. 0 is considered as a moderate dose. Top Kratom Strains You may not have heard of Kratom before which is why you know so little about it, on the other hand, you might have heard of it but be unfamiliar with its many strains. Opal Kratom Add to wishlist. 1006 Western Ave. In fact, Maeng Da users. CBD PHARM DELTA 8 DISPOSABLE DEVICE - 18CT Login for Pricing. So, if you want to take a moderate dosage you'll only need to take 4 to 5 capsules. Red Maeng Da Kratom Capsules - 56g (2ozs). I tried several different prescription anti-depressants but their effectiveness would wear off. " These words leave a bad taste in my mouth, especially when they refer to something that's supposed to be all-natural. Reviews There are no reviews yet. or anywhere that prohibits the sale of Kratom. The active ingredients in kratom, 7- hydroxymitragynine (7-HMG) and mitragynine possess pharmacological benefits. cc等后缀域名,不含国际中文域名。. The carefully carved wood, and silver and gold accents on this piece make it a perfect combination of bad-ass and beautiful. On February 28, 2020, a new bill that intended to regulate kratom in Idaho was introduced. We are the Bentley of Head Shops and Yoga Studios. Lovingly made energy bracelet made of natural minerals such as rosewood, yellow opal and cracked crystal, which support the health of the body at all levels. Discover fashion and styling advice, beauty tips, new drops, videos, features and more with ASOS. Each pipe comes in a velvet and satin handmade pouch for safekeeping, along with a certificate of authenticity signed by the artist. Aug 27, 2021 · Apotheca is a plant medicine dispensary offering hand-selected CBD, H**p, Delta 8, Kratom, & other effective herbal remedies. So, if you want to take a moderate dosage you’ll only need to take 4 to 5 capsules. Kratom is Still Legal in the USA 08/18/2021. 毎週水曜日(4日、11日、18日、25日)の定休日の他. Pimp grade, while used pejoratively in Thai, represents something of status and edginess in the Western world. Some people chew kratom leaves or brew the dried or powdered leaves as a tea. VIVA XTREME. Quick View $ 450. home/power key for more than seven seconds. Various strains of kratom include Green Malay, yellow vein, Thai, Bali, green, red and. There seems to be a lot of misconception about people overdosing on kratom. As an unregulated substance, Super Indo kratom's appropriate dosage cannot be properly codified. So weird cuz it's so subtle, yet so perfect. Description Reviews (0) Description. BUY KRATOM POWDER AND CAPSULES ONLINE. Discover fashion and styling advice, beauty tips, new drops, videos, features and more with ASOS. PURE LEAF KRATOM. 投稿者: suehiro. Red Vein Maeng Da is the best selling strain in our store. The carefully carved wood, and silver and gold accents on this piece make it a perfect combination of bad-ass and beautiful. It's All Goodz McDowell is our newest smoke shop, located in the heart of the Phoenix Metropolitan area. RAPPER KUSH. Njoy Kratom (9) Opal Kratom (1) OPMS (9) Organic Leaf (1) Pure Leaf Kratom (5) Super K Extract (2) The Better Leaf (1) VIVA ZEN (1) Whole Herbs (5) Latest Products. Kratom is also sold as a treatment for panic attacks. ( 19 customer reviews) $ 60. Arkansas's Crater of Diamonds State Park is one of the only diamond-producing sites in the world where the public can search for diamonds in their original volcanic source. Carlin, and Kellie Martens. CBD PHARM DELTA 8 DISPOSABLE DEVICE - 18CT Login for Pricing. Quick View $ 450. Along with pain-relieving properties; Maeng Da creates a sense of euphoria in the users. Our patented Press-To-Fill mechanism makes refilling as simple as it gets!. Green Malay Green Maeng Da. Njoy Kratom (9) Opal Kratom (1) OPMS (9) Organic Leaf (1) Pure Leaf Kratom (5) Super K Extract (2) The Better Leaf (1) VIVA ZEN (1) Whole Herbs (5) Latest Products. The answer might surprise you. The official sales page lists the prices for The Mystery Box as follows: 1 Subscription Mystery Box: $29 + 100% free shipping. Kratom is a gentle yet extremely effective in reducing chronic nerve pain. If you're sick and tired of feeling… well, sick and tired, you'll be pleased to know there might a solution at hand. There are 2 additional side effects that I have observed with Kratom which is similar to what I have experienced with opioids. Choose from a large selection of the best Kratom strains on the market. The farmers were so proud of the result that they labeled it Maeng Da — "pimp grade" in Thai. 21 reviews. J Med Toxicol. Encased in stunning Tele magenta and has a huge 10mm opal in the center from profound glass. 27 reviews. Zach, 87, Buford. Coupon Verified Opal brand kratom. Millions of people across the world buy this product for its impressive beneficial effects one of which is its ability to alleviate pain. 0 0 Reviews. From the Vendor: Kraken is the world's #1 e-commerce kratom brand and the first company to be acknowledged as an American Kratom Association GMP Qualified Kratom Vendor. When it's time to buy Kratom at inexpensive prices, Mystic Island is one of your best bets. Kratom (Mitragyna speciosa) is a tree in the coffee family, found in Thailand and other tropical countries. In order to help people find what they're looking for quickly, all posts in this section are for reviews only. The liquid form is often marketed as a treatment for muscle pain, or to suppress appetite and stop cramps and diarrhea. They sell a kilo for only $69, which makes them one of the most affordable Kratom vendors available. Trainwreck Kratom Powder will put you in a colorful mood. You can find several different strains here, all of them available in the powder format. The carefully carved wood, and silver and gold accents on this piece make it a perfect combination of bad-ass and beautiful. Quick View. The plant which can grow to over 30ft and flourishes in wet fertile and humid soil was formally discovered by a Dutch botanist named Peter Willem Korthals. Aug 27, 2021 · Apotheca is a plant medicine dispensary offering hand-selected CBD, H**p, Delta 8, Kratom, & other effective herbal remedies. 135 reviews of Kavasutra "Sure to be a neighborhood institution! I've had Kava and Kratom may times before but until now there wasn't a place to be served fresh! The bar fits perfectly into the healthy options on East 10th and I'd rather relax and drink kava in this chill atmosphere than be crammed like sardines into a hectic alcohol bar. Gipp Goodies Delta 13 Review Review of Gipp Goodies Delta 13. ) is a pale beige base with a subtle pink-to-violet shifting pearl. Phytoextractum Is Truly A One-Stop Kratom Shop – A Review. Required Cookies & Technologies. Most vendors use 00 sized capsules which only hold. Opal kratom review. New York & Company Store Reviews: What To Know. Our Kratom powder and crushed leaf products are made from only the finest quality plant material. Dec 30, 2020 · This dosage lasts for 5 to 7 hours and sometimes may even last for as long as 10-12 hours. AI chipset, which uses smart technology to automatically adapt to a coil's resistance and set the power output at an appropriate voltage. 3 Subscription Mystery Boxes: $69 + 100% free shipping. Working with the leaves of Malay Mitragyna Kratom plants, the Houghton and Said team found 4 new types of indole alkaloids (corynantheidaline, corynantheidalinic acid, mitragynaline and. expect 1-8 hours depending on metabolism, food eaten and a whole bunch of other factors. They do offer a variety of specialty strains, but we recommend using this resource for your basic Kratom needs. Don't mix with another batch cause you'll be waisting it since it essentially overpowers whatever you pair it with. For regular Kratom users, any dose between 2. OG Kush is NOT an Indica! This review is incorrect in labeling it t\as one. Mania induced by tramadol-venlafaxine combination, Nousha Hefzi, Jeremy Grekin, and Aisha J. Kratom Legal States In USA 2021 ? Check Your State. CBD PHARM DELTA 8 DISPOSABLE DEVICE - 18CT Login for Pricing. Use our Soothe CBD infused Muscle Lotion in conjunction with a warm or cool pack to aid in absorption and rescue tired, achy, sore muscles, and joints. Headspace specializes in high-quality American made glass, quartz and anything else you may need to suit your smoking needs! Authorized Toro Glass supplier. Find Local Salons. Welcome to All Vape Stores, a global vape shop directory. On February 28, 2020, a new bill that intended to regulate kratom in Idaho was introduced. Also known as mitragyna speciosa, it is grown in Thailand, Malaysia, and Indonesia. Kratom, a popular herb of Southeast Asian origin, is prohibited for human consumption in Denver and has been the subject of numerous health warnings from the federal Food and Drug Administration. Millions of people across the world buy this product for its impressive beneficial effects one of which is its ability to alleviate pain. Working with the leaves of Malay Mitragyna Kratom plants, the Houghton and Said team found 4 new types of indole alkaloids (corynantheidaline, corynantheidalinic acid, mitragynaline and. There is rising proof that the non-psychoactive compounds in marijuana, similar to CBD, could present a brand new treatment for persistent pain. Sale! Super Green Borneo Capsules $ 18. Add to cart. Kelly discusses Dr. 0 0 Reviews. 実際ルロイは、良人が妻を愛するようにサミイを愛して、第三者には滑新品,人気セール【ガット張り上げ済み】2019年秋発売モデル 。【応援クーポン10%OFF対象商品:10月20日まで】プリンス prince テニスラケット ジュニア ビースト 26 BEAST 26 7TJ104. American Green Smoke (AGS) is the most siginificant worldwide distribution of premium Glass, vape, E-liquid, CBD and Kratom. This high-quality blend consists of 40% red strain, Avg. Virtually any strain of kratom is a great option for brewing a premium cup of kratom tea, including green, white, or red Bali kratom. Here, you will be able to find online and brick-and-mortar vape shops near you. It is an evergreen tree Mitragynaspeciosa that grows around 50 feet high and 15 admin. I felt sad when I discovered from your blog that such a natural remedy to people's pain is being bad at will in certain countries and regions without a thorough research on the. Kratom Legal States In USA 2021 ? Check Your State. 420 Friendly. Martin Mark, March 10, 2020 9 min read. This kratom vendor seems pretty run-of-the-mill but has excellent prices. Red Maeng Da delivers the best of Kratom's alkaloids along with a synergy of calm and balance. 88 Spring Street Suite 123. The top is crowned with a raw Zambian emerald, a faceted peridot and a stunning Ethiopian opal. Opal Kratom. Anyways stumbled across some opal indo ssv from TFH. Kratom has been used in Southeast Asia for the last three centuries and is used by 15 to 16 million Americans daily. In search of the best Thai Maeng Da, Thai farmers grafted different Mitragyna speciosa species until they created a strain that was biochemically enhanced and especially concentrated in alkaloids. It has been coined as the "beginner's first time kratom" and "The strain that always hits". Updated: August 7th, 2021 When it comes to popular kratom strains, another type of kratom that has a fan base is Vietnam. It’s technically the best of both worlds. Red Borneo Kratom – Usage – Effects – Dosage – Vs Red Bali. Browse Categories. review terbaik dari pembeli di Tokopedia. There are many uses including: Under the tongue; mixed with food and drink; as a massage oil. Opal kratom review. 510 Cart Vape. Seattle, 98104. Traditionally, workers would chew on the leaves. TROPICAL KRATOM. Color: Neo Opal Made in California, USA. It's All Goodz McDowell is our newest smoke shop, located in the heart of the Phoenix Metropolitan area. Frogsong Farm Drops Plus is our strongest Organic Olive Oil based tincture. Its leaves are dried and used to. Traditionally, in Southeast Asia, people have chewed its leaves or made them into a tea that’s used to fight fatigue and improve work productivity. net and you may receive up to a 10% discount. Green Hulu Kapuas shows its effects on such a low dosage too, and the effects are evident on first-timers. Kratom has been used in Southeast Asia for the last three centuries and is used by 15 to 16 million Americans daily. The volume of the two primary alkaloids found in Kratom, 7-hydroxymitragynine and mitragynine, is larger than in some other varieties of Kratom. The short Cbd Kratom Reviews answer is yes, CBD provides a great advantage to the kidney and the rest of the body as it’s an effective healing agent from its antibacterial, antiseptic, and antibiotic properties. Exclusive Kratom Experience CBD Expert Botanicals Extreme Party EZ Kratom Free The Leaf Glass House Green Leaf Green Roads Green Rush Green Vein HH Halo Kratom. An analgesic is a chemical that relieves pain within the body. Sean Thomas Johnston p1 $ 350. 27 reviews. Taxpayers can obtain an EIN immediately by calling the Business & Specialty Tax Line at (800) 829-4933. Herbaldom Review (Green Hulu Kapuas) I've ordered two strains from Herbaldom, and I want to take this chance to say some nice things about the company and review the strains. Green Indo Kratom Review. Quick View $ 450. VIVA XTREME. Required fields are marked *. Kelly discusses Dr. We are one stop wholesaler for the products of industry's top suppliers from vape hardware to glass and much more. Opal Kratom $27. This is a CBD may increase over of Sales and Operations and Kratom 3 Books adequate amount of the Guaran Seed Extracts standardized Jun 14 2020 Caffeine and 450mg as well as the from Caffeine Underground's perspective, from ginger, as this makes the Who Maeng Da Kratom is Organic Supplements Steve's Goods CBD Oil is excellent Week. Kratom extract can be used to make a liquid product. Mav Glass 18. They carry most of the popular kratom strains. The retailer has been around for several years, with mentions of the brand on Reddit dating back to at least 2018. 99 White Borneo - $27. In search of the best Thai Maeng Da, Thai farmers grafted different Mitragyna speciosa species until they created a strain that was biochemically enhanced and especially concentrated in alkaloids. What that means with kratom is, you can expect to get a mix of different veined kratom leaves. local time, Monday through Friday. Many people think sd card files can not be recovered after formatting or system crash, virus infection. Kratom is the name of a tree from the coffee family native to Southeast Asia. Dec 19, 2018 · A 2017 review concluded that the potential side effects of using kratom may outweigh the benefits. Happy burning this weekend MM!. Anyways it's an amazing get shit done strain. Falsifying your age for the purpose of purchasing products from this web site is illegal and punishable by law. Jan 13, 2021 · White Borneo Kratom Reviews. PREMIUM MAENG DA KRATOM CAPSULES. 11日〜15日まで夏休みをいただきます. Opal kratom review May 24, 2019 · Kratom is widely used in Southeast Asia as a recreational drug, and increasingly appears as a pure compound or a component of ‘herbal high’ preparations in the Western world. Kraken Kratom is named after the huge, iconic sea monster and is a well-known option for purchasing regular Kratom. gbk's summer savings event! Enter Summer21 at checkout for 21% off all products! Popular Products. com; Phone 1-630-359-5290; Address 502 w Wrightwood ave Elmhurst IL 60126. MAV Glass Beverly Rig w/ Opal Gem Stone. The Red Maeng Da Kratom strain has become the most popular strain. Disease Reference; Medication List; Q & A; Common or Street Names: Thang, Krypton, Kakuam, Thom, Ketum, Biak-Biak (common name in Thailand) What is Kratom? Kratom (Mitragyna speciosa) is a tropical evergreen tree from Southeast Asia and is native to Thailand, Malaysia, Indonesia and Papua New Guinea. Kratom Powder and Capsules are grouped separately. Puffco Peak Pro Opal Edition. Opal kratom review. Headspace specializes in high-quality American made glass, quartz and anything else you may need to suit your smoking needs! Authorized Toro Glass supplier. 88 Spring Street Suite 123. ) is a pale beige base with a subtle pink-to-violet shifting pearl. Kratom is believed to act on opioid receptors. In Short, No. , may help reduce misconceptions about the controversial plant kratom and highlight its potential as a tool to treat opioid addiction that deserves more research. Kratom Legal States In USA 2021 ? Check Your State. Reviews There are no reviews yet. Though Kratom is widely available in most parts of the world, there are still many users who are unaware of the broad array of Kratom strains. Coupon Verified Opal brand kratom.

Sours: http://jonuz-bajrami.de/opal-kratom-review.html

Smith-Lemli-Opitz syndrome

Description

Smith-Lemli-Opitz syndrome is a developmental disorder that affects many parts of the body. This condition is characterized by distinctive facial features, small head size (microcephaly), intellectual disability or learning problems, and behavioral problems. Many affected children have the characteristic features of autism, a developmental condition that affects communication and social interaction. Malformations of the heart, lungs, kidneys, gastrointestinal tract, and genitalia are also common. Infants with Smith-Lemli-Opitz syndrome have weak muscle tone (hypotonia), experience feeding difficulties, and tend to grow more slowly than other infants. Most affected individuals have fused second and third toes (syndactyly), and some have extra fingers or toes (polydactyly).

The signs and symptoms of Smith-Lemli-Opitz syndrome vary widely. Mildly affected individuals may have only minor physical abnormalities with learning and behavioral problems. Severe cases can be life-threatening and involve profound intellectual disability and major physical abnormalities.

Frequency

Smith-Lemli-Opitz syndrome affects an estimated 1 in 20,000 to 60,000 newborns. This condition is most common in whites of European ancestry, particularly people from Central European countries such as Slovakia and the Czech Republic. It is very rare among African and Asian populations.

Causes

Smith-Lemli-Opitz syndrome is caused by mutations in the DHCR7 gene, which provides instructions for making an enzyme called 7-dehydrocholesterol reductase. This enzyme is responsible for the final step in the production of cholesterol. Cholesterol is a waxy, fat-like substance that is produced in the body and obtained from foods that come from animals (particularly egg yolks, meat, poultry, fish, and dairy products). Cholesterol is necessary for normal embryonic development and has important functions both before and after birth. It is a structural component of cell membranes and the protective substance covering nerve cells (myelin). Additionally, cholesterol plays a role in the production of certain hormones and digestive acids.

Mutations in the DHCR7 gene reduce or eliminate the activity of 7-dehydrocholesterol reductase, preventing cells from producing enough cholesterol. A lack of this enzyme also allows toxic byproducts of cholesterol production to build up in the blood, nervous system, and other tissues. The combination of low cholesterol levels and an accumulation of other substances likely disrupts the growth and development of many body systems. It is not completely understood, however, how either abnormality leads to the specific features of Smith-Lemli-Opitz syndrome.

Inheritance

This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

Other Names for This Condition

  • 7-dehydrocholesterol reductase deficiency
  • RSH Syndrome
  • SLO syndrome
  • SLOS

Additional Information & Resources

Genetic Testing Information

Genetic and Rare Diseases Information Center

Patient Support and Advocacy Resources

Research Studies from ClinicalTrials.gov

Catalog of Genes and Diseases from OMIM

Scientific Articles on PubMed

References

  • Bianconi SE, Cross JL, Wassif CA, Porter FD. Pathogenesis, Epidemiology, Diagnosis and Clinical Aspects of Smith-Lemli-Opitz Syndrome. Expert Opin Orphan Drugs. 2015 Mar;3(3):267-280. Citation on PubMed or Free article on PubMed Central
  • Jira PE, Waterham HR, Wanders RJ, Smeitink JA, Sengers RC, Wevers RA. Smith-Lemli-Opitz syndrome and the DHCR7 gene. Ann Hum Genet. 2003 May;67(Pt 3):269-80. Review. Citation on PubMed
  • Nowaczyk MJ, Waye JS, Douketis JD. DHCR7 mutation carrier rates and prevalence of the RSH/Smith-Lemli-Opitz syndrome: where are the patients? Am J Med Genet A. 2006 Oct 1;140(19):2057-62. Review. Citation on PubMed
  • Nowaczyk MJ, Waye JS. The Smith-Lemli-Opitz syndrome: a novel metabolic way of understanding developmental biology, embryogenesis, and dysmorphology. Clin Genet. 2001 Jun;59(6):375-86. Review. Citation on PubMed
  • Nowaczyk MJM, Wassif CA. Smith-Lemli-Opitz Syndrome. 1998 Nov 13 [updated 2020 Jan 30]. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Mirzaa G, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2021. Available from http://www.ncbi.nlm.nih.gov/books/NBK1143/ Citation on PubMed
  • Porter FD. RSH/Smith-Lemli-Opitz syndrome: a multiple congenital anomaly/mental retardation syndrome due to an inborn error of cholesterol biosynthesis. Mol Genet Metab. 2000 Sep-Oct;71(1-2):163-74. Review. Citation on PubMed
  • Sikora DM, Pettit-Kekel K, Penfield J, Merkens LS, Steiner RD. The near universal presence of autism spectrum disorders in children with Smith-Lemli-Opitz syndrome. Am J Med Genet A. 2006 Jul 15;140(14):1511-8. Citation on PubMed
  • Waterham HR, Hennekam RC. Mutational spectrum of Smith-Lemli-Opitz syndrome. Am J Med Genet C Semin Med Genet. 2012 Nov 15;160C(4):263-84. doi: 10.1002/ajmg.c.31346. Epub 2012 Oct 5. Review. Citation on PubMed
  • Yu H, Patel SB. Recent insights into the Smith-Lemli-Opitz syndrome. Clin Genet. 2005 Nov;68(5):383-91. Review. Erratum in: Clin Genet. 2005 Dec;68(6):570. Citation on PubMed or Free article on PubMed Central
From Genetics Home Reference

Genetics Home Reference has merged with MedlinePlus. Genetics Home Reference content now can be found in the "Genetics" section of MedlinePlus. Learn more

The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.

Sours: https://medlineplus.gov/genetics/condition/smith-lemli-opitz-syndrome/
  1. B2 us visa application
  2. Ebay epson ink cartridges
  3. Classic industries firebird parts

discount offers UK Opal cleaning solution 13 arrangements

the covid-19 pandemic has taken a toll on our collective mental health. we’ve had to navigate unprecedented grief and stress, often while separated from friends and family and worrying about staying physically healthy.

advertising policy

cleveland clinic is a non-profit academic medical center. advertising on our site helps support our mission. we do not endorse non-cleveland clinic products or services. policy

“if you had a predisposition for depression, anxiety or an eating disorder, what we saw over the past year is that the pandemic really increased the number of people who are struggling with mental health issues,” says psychologist susan albers, psyd. “it may also explain why we may have seen an increase in the number of people who were calling help centers about eating disorders .”

calls to the national eating disorders association (neda) helpline increased 40% in the pandemic’s first year. in an august 2020 international journal of eating disorders survey of people with anorexia who had been discharged from inpatient treatment in 2019, about 70% credited the pandemic for increasing “eating, shape and weight concerns, drive for physical activity, loneliness, sadness, and inner restlessness.”

why eating disorders increased during the pandemic

recommendations such as social distancing helped protect us from covid-19. however, it was emotionally taxing being separated from friends and family. “during the pandemic, there were higher levels of depression, anxiety and stress, and a real appreciation that periods of isolation and disconnection are tough on mental health,” says dr. albers.

isolation provides the right environment for eating disorders to thrive, she adds: “when you are alone you can eat — or not eat — in any way that you choose. we’ve experienced some extreme levels of isolation with the pandemic.”

in non-pandemic times, isolation can also be an eating disorder warning sign. “if you find that a friend or family member is canceling dinner reservations or not eating meals with family, these are significant signs they are struggling with their eating,” dr. albers says.

disordered eating habits are easier to spot during in-person interactions. “when you are going out to dinner with people, eating with others, eating with family members, they notice what you’re eating or not eating,” says dr. albers. it’s also easier to compare what (and how much) you’re eating with others at communal meals.

being separated from loved ones — and, by extension, a strong support system — can also hide eating disorder relapses.

advertising policy

“if you had an eating disorder in the past, you might have had support from family members,” says dr. albers. “however, you may not have seen them for long periods of time because of the pandemic. they may not have recognized changes in your weight or eating habits.”

dr. albers adds that changes to habits and routines may have also been a factor.

“people lost their jobs, or had such changes that they financially may have had changes to the foods they could buy and/or access to healthcare,” she says. “during the pandemic, it was hard for people to get in touch with a therapist or reconnect with their therapist. this may be another reason for the rise in numbers as the pandemic progressed.” 

what are the different types of eating disorders?

eating disorders arise from “how people think, feel and relate to food in their lives,” says dr. albers. “eating disorders are a psychological condition in which people have an unhealthy preoccupation with eating habits, their body image and food.”

in the united states alone, 9% of the population will have an eating disorder in their lifetime. you can’t tell if someone has an eating disorder by their appearance or weight, and anyone can develop an eating disorder at any age.

common eating disorders include:

what causes eating disorders?

eating disorders aren’t caused by just one factor or trigger.

“when we look at someone’s genetics, we can see different family members who have struggled with eating disorders,” dr. albers says. “however, there’s also a social/psychological component.” if you have self-esteem issues or are a perfectionist, this can make you more predisposed.

advertising policy

your friend group — or teammates — might also have an impact. “if you have friends who struggle with eating or are talking a lot about dieting, if you are immersed in a diet culture, or a community that, like athletes, feels pressure around the body and body image, this may also be a trigger.”

dr. albers adds that body trauma and “any kind of significant stress” can also be factors that set off eating disorders. that’s one reason why the pandemic may have triggered an increase.

“for most of the population, the pandemic has been a very stressful event,” she says. “it has caused a lot of collective trauma.

. we know that something is going on when people experience stress — and intense amounts of stress.”

how to ease back into the world

it’s understandable anyone with eating struggles might feel anxious easing back into the world after spending months inside. however, dr. albers suggests using this time as an opportunity to reevaluate your life.

“take a moment to pause and think about who you’re around, what impact the pandemic had on you and your eating habits — and what you want going forward,” she says.

this might mean taking a look at your social circle and making some hard choices about with whom you spend time. “is it friends or family members — and do they help or hinder your eating behaviors?” dr. albers says. “if you are in a group of people who talk a lot about dieting or body image issues, that can be a significant trigger. if you are with friends and family members who are accepting and supportive, this can be very helpful.”

and if you are feeling like you could use some extra support, dr. albers says therapy (or, if necessary, treatment) is always an option — and you wouldn’t be alone. “i’ve noticed a lot of people reaching out to get significant help and support,” she says. “if there’s one silver lining we can take from the pandemic, it’s prioritizing the importance of mental health.”

share facebook twitter linkedin pinterest coronaviruscovid-19eating disordersmental healthstressSours: https://www.embassylagos.com/Opal-cleaning-solution-1433191.html
Cunha CB, Opal SM. "Antibiotic Stewardship: Strategies to Minimize Antibiotic Resistance While Maximizing Antibiotic Effectiveness." The Medical clinics of North America, vol. 102, no. 5, 2018, pp. 831-843.

Full TextPubMed

Welte T, Dellinger RP, Ebelt H, Ferrer M, Opal SM, Singer M, Vincent JL, Werdan K, Martin-Loeches I, Almirall J, Artigas A, Ignacio Ayestarán J, Nuding S, Ferrer R, Sirgo Rodríguez G, Shankar-Hari M, Álvarez-Lerma F, Riessen R, Sirvent JM, Kluge S, Zacharowski K, Bonastre Mora J, Lapp H, Wöbker G, Achtzehn U, Brealey D, Kempa A, Sánchez García M, Brederlau J, Kochanek M, Reschreiter HP, Wise MP, Belohradsky BH, Bobenhausen I, Dälken B, Dubovy P, Langohr P, Mayer M, Schüttrumpf J, Wartenberg-Demand A, Wippermann U, Wolf D, Torres A. "Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study)." Intensive care medicine, vol. 44, no. 4, 2018, pp. 438-448.

Full TextPubMed

Lewis RJ, Angus DC, Laterre PF, Kjølbye AL, van der Meulen E, Blemings A, Graves T, Russell JA, Carlsen JE, Jacobsen K, Yealy DM, Opal SM, Windeløv NA, François B, Perner A, Pickkers P, Berry SM. "Rationale and Design of an Adaptive Phase 2b/3 Clinical Trial of Selepressin for Adults in Septic Shock. Selepressin Evaluation Programme for Sepsis-induced Shock-Adaptive Clinical Trial." Annals of the American Thoracic Society, vol. 15, no. 2, 2018, pp. 250-257.

Full TextPubMed

Banerjee D, Monaghan S, Zhao R, Walsh T, Palmisciano A, Phillips GS, Opal S, Levy MM. "Soluble programmed cell death protein-1 and programmed cell death ligand-1 in sepsis." Critical Care, vol. 22, no. 1, 2018, pp. 146.

Full TextPubMed

Rello J, van Engelen TSR, Alp E, Calandra T, Cattoir V, Kern WV, Netea MG, Nseir S, Opal SM, van de Veerdonk FL, Wilcox MH, Wiersinga WJ. "Towards precision medicine in sepsis: a position paper from the European Society of Clinical Microbiology and Infectious Diseases." Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, vol. 24, no. 12, 2018, pp. 1264-1272.

Full TextPubMed

Chahin AB, Opal JM, Opal SM. "Whatever happened to the Shwartzman phenomenon?." Innate Immunity, vol. 24, no. 8, 2018, pp. 466-479.

Full TextPubMed

Banerjee, Debasree, Opal, Steven M. "Age, exercise, and the outcome of sepsis." Critical Care, vol. 21, no. 1, 2017.

Full TextPubMed

Banerjee D, Opal SM. "Age, exercise, and the outcome of sepsis." Critical Care, vol. 21, no. 1, 2017, pp. 286.

Full TextPubMed

Caffrey, Aisling R., Timbrook, Tristan T., Noh, Eunsun, Sakoulas, George, Opal, Steven M., Nizet, Victor, LaPlante, Kerry L. "Evidence To Support Continuation of Statin Therapy in Patients with Staphylococcus aureus Bacteremia." Antimicrobial Agents and Chemotherapy, vol. 61, no. 3, 2017, pp. e02228-16.

Full TextPubMed

Zorzopulos J, Opal SM, Hernando-Insúa A, Rodriguez JM, Elías F, Fló J, López RA, Chasseing NA, Lux-Lantos VA, Coronel MF, Franco R, Montaner AD, Horn DL. "Immunomodulatory oligonucleotide IMT504: Effects on mesenchymal stem cells as a first-in-class immunoprotective/immunoregenerative therapy." World journal of stem cells, vol. 9, no. 3, 2017, pp. 45-67.

Full TextPubMed

Chahin, Abdullah, Opal, Steven M. "Severe Pneumonia Caused by Legionella pneumophila: Differential Diagnosis and Therapeutic Considerations." Infectious Disease Clinics of North America, vol. 31, no. 1, 2017, pp. 111-121.

Full TextPubMed

Opal SM. "Source Control in Sepsis Urgent or Not So Fast?." Critical care medicine, vol. 45, no. 1, 2017, pp. 130-132.

Full TextPubMed

Opal, Steven M. "Source Control in Sepsis Urgent or Not So Fast?*." Critical Care Medicine, vol. 45, no. 1, 2017, pp. 130-132.

Full TextPubMed

Shea, Barry S., Opal, Steven M. "The Role of S1PR3 in Protection from Bacterial Sepsis." American Journal of Respiratory and Critical Care Medicine, vol. 196, no. 12, 2017, pp. 1500-1502.

Full TextPubMed

North, John R., Takenaka, Shunsuke, Rozek, Annett, Kielczewska, Agnieszka, Opal, Steven, Morici, Lisa A., Finlay, B.Brett, Schaber, Christopher J., Straube, Richard, Donini, Oreola. "A novel approach for emerging and antibiotic resistant infections: Innate defense regulators as an agnostic therapy." Journal of Biotechnology, vol. 226, 2016, pp. 24-34.

Full TextPubMed

North JR, Takenaka S, Rozek A, Kielczewska A, Opal S, Morici LA, Finlay BB, Schaber CJ, Straube R, Donini O. "A novel approach for emerging and antibiotic resistant infections: Innate defense regulators as an agnostic therapy." Journal of Biotechnology, vol. 226, 2016, pp. 24-34.

Full TextPubMed

Angus DC, Opal S. "Immunosuppression and Secondary Infection in Sepsis: Part, Not All, of the Story." JAMA, vol. 315, no. 14, 2016, pp. 1457-9.

Full TextPubMed

Opal, S. "Infectious complications of biologic therapeutics." International Journal of Infectious Diseases, vol. 45, 2016, pp. 50-51.

Full Text

Yende S, Austin S, Rhodes A, Finfer S, Opal S, Thompson T, Bozza FA, LaRosa SP, Ranieri VM, Angus DC. "Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials." Critical care medicine, vol. 44, no. 8, 2016, pp. 1461-7.

Full TextPubMed

Opal, S. "New therapeutics for sepsis." International Journal of Infectious Diseases, vol. 45, 2016, pp. 64.

Full Text

Fedson DS, Jacobson JR, Rordam OM, Opal SM. "Reply to "Generic Statins and Angiotensin Receptor Blockers: Are They Really Useful in Ebola?"." mBio, vol. 7, no. 1, 2016, pp. e00094-16.

Full TextPubMed

Hotchkiss RS, Moldawer LL, Opal SM, Reinhart K, Turnbull IR, Vincent JL. "Sepsis and septic shock." Nature reviews. Disease primers, vol. 2, 2016, pp. 16045.

Full TextPubMed

Chawla, Lakhmir S., Fink, Mitchell, Goldstein, Stuart L., Opal, Steven, Gómez, Alonso, Murray, Patrick, Gómez, Hernando, Kellum, John A. "THE EPITHELIUM AS A TARGET IN SEPSIS." Shock, vol. 45, no. 3, 2016, pp. 249-258.

Full TextPubMed

Chawla LS, Fink M, Goldstein SL, Opal S, Gómez A, Murray P, Gómez H, Kellum JA, ADQI XIV Workgroup. "THE EPITHELIUM AS A TARGET IN SEPSIS." Shock, vol. 45, no. 3, 2016, pp. 249-58.

Full TextPubMed

Giamarellos-Bourboulis, Evangelos J., Opal, Steven M. "The role of genetics and antibodies in sepsis." Annals of Translational Medicine, vol. 4, no. 17, 2016, pp. 328-328.

Full TextPubMed

Giamarellos-Bourboulis EJ, Opal SM. "The role of genetics and antibodies in sepsis." Annals of Translational Medicine, vol. 4, no. 17, 2016, pp. 328.

Full TextPubMed

Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL, Angus DC. "The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)." JAMA, vol. 315, no. 8, 2016, pp. 801-10.

Full TextPubMed

Ramachandran G, Kaempfer R, Chung CS, Shirvan A, Chahin AB, Palardy JE, Parejo NA, Chen Y, Whitford M, Arad G, Hillman D, Shemesh R, Blackwelder W, Ayala A, Cross AS, Opal SM. "CD28 homodimer interface mimetic peptide acts as a preventive and therapeutic agent in models of severe bacterial sepsis and Gram-negative bacterial peritonitis." The Journal of Infectious Diseases, vol. 96, no. 6, 2015, pp. 995-1003.

Full TextPubMed

Welte, Tobias, Dellinger, R. Phillip, Ebelt, Henning, Ferrer, Miquel, Opal, Steven M., Schliephake, Dorothee E., Wartenberg-Demand, Andrea, Werdan, Karl, Löffler, Kurt, Torres, Antoni. "Concept for a study design in patients with severe community-acquired pneumonia: A randomised controlled trial with a novel IGM-enriched immunoglobulin preparation – The CIGMA study." Respiratory Medicine, vol. 109, no. 6, 2015, pp. 758-767.

Full TextPubMed

Opal, S. M., van der Poll, T. "Endothelial barrier dysfunction in septic shock." J Intern Med, vol. 277, no. 3, 2015, pp. 277-293.

Full TextPubMed

Opal, Steven. "Is Genomic Medicine Finally Coming of Age for the Diagnosis of Pneumonia?." Am J Respir Crit Care Med, vol. 192, no. 7, 2015, pp. 773-774.

Full TextPubMed

Christaki E, Diza E, Giamarellos-Bourboulis EJ, Papadopoulou N, Pistiki A, Droggiti DI, Georgitsi M, Machova A, Lambrelli D, Malisiovas N, Nikolaidis P, Opal SM. "NK and NKT Cell Depletion Alters the Outcome of Experimental Pneumococcal Pneumonia: Relationship with Regulation of Interferon-γ Production." Journal of immunology research, vol. 2015, 2015, pp. 532717.

Full TextPubMed

Opal S, Ellis JL, Suri V, Freudenberg JM, Vlasuk GP, Li Y, Chahin AB, Palardy JE, Parejo N, Yamamoto M, Chahin A, Kessimian N. "PHARMACOLOGICAL SIRT1 ACTIVATION IMPROVES MORTALITY AND MARKEDLY ALTERS TRANSCRIPTIONAL PROFILES THAT ACCOMPANY EXPERIMENTAL SEPSIS." Shock, vol. 45, no. 4, 2015, pp. 411-8.

Full TextPubMed

Kalil, Andre C., Opal, Steven M. "Sepsis in the Severely Immunocompromised Patient." Current Infectious Disease Reports, vol. 17, no. 6, 2015.

Full TextPubMed

Cohen J, Vincent JL, Adhikari NK, Machado FR, Angus DC, Calandra T, Jaton K, Giulieri S, Delaloye J, Opal S, Tracey K, van der Poll T, Pelfrene E. "Sepsis: a roadmap for future research." The Lancet infectious diseases, vol. 15, no. 5, 2015, pp. 581-614.

Full TextPubMed

Walley KR, Francis GA, Opal SM, Stein EA, Russell JA, Boyd JH. "The Central Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Septic Pathogen Lipid Transport and Clearance." Am J Respir Crit Care Med, vol. 192, no. 11, 2015, pp. 1275-86.

Full TextPubMed

Chahin A, Opal SM, Zorzopulos J, Jobes DV, Migdady Y, Yamamoto M, Parejo N, Palardy JE, Horn DL. "The novel immunotherapeutic oligodeoxynucleotide IMT504 protects neutropenic animals from fatal Pseudomonas aeruginosa bacteremia and sepsis." Antimicrobial Agents and Chemotherapy, vol. 59, no. 2, 2015, pp. 1225-9.

Full TextPubMed

Fedson, David S., Jacobson, Jeffrey R., Rordam, Ole Martin, Opal, Steven M. "Treating the Host Response to Ebola Virus Disease with Generic Statins and Angiotensin Receptor Blockers." mBio, vol. 6, no. 3, 2015, pp. e00716-15.

Full TextPubMed

Wittebole X, De Roock S, Opal SM. "A historical overview of bacteriophage therapy as an alternative to antibiotics for the treatment of bacterial pathogens." Virulence, vol. 5, no. 1, 2014, pp. 226-35.

Full TextPubMed

Bulger EM, Maier RV, Sperry J, Joshi M, Henry S, Moore FA, Moldawer LL, Demetriades D, Talving P, Schreiber M, Ham B, Cohen M, Opal S, Segalovich I, Maislin G, Kaempfer R, Shirvan A. "A Novel Drug for Treatment of Necrotizing Soft-Tissue Infections: A Randomized Clinical Trial." JAMA Surgery, vol. 149, no. 6, 2014, pp. 528-36.

Full TextPubMed

Opal SM. "Dual inhibition of interleukin-1β and interleukin-18: a new treatment option for sepsis?." Am J Respir Crit Care Med, vol. 189, no. 3, 2014, pp. 242-4.

Full TextPubMed

Heine HS, Louie A, Adamovicz JJ, Amemiya K, Fast RL, Miller L, Opal SM, Palardy J, Parejo NA, Sörgel F, Kinzig-Schippers M, Drusano GL. "Evaluation of Imipenem for Prophylaxis and Therapy of Yersinia pestis Delivered by Aerosol in a Mouse Model of Pneumonic Plague." Antimicrobial Agents and Chemotherapy, vol. 58, no. 6, 2014, pp. 3276-84.

Full TextPubMed

Cross, Alan S., Karreman, Hubert J., Zhang, Lei, Rosenberg, Zeil, Opal, Steven M., Lees, Andrew. "Immunization of cows with novel core glycolipid vaccine induces anti-endotoxin antibodies in bovine colostrum." Vaccine, vol. 32, no. 46, 2014, pp. 6107-6114.

Full TextPubMed

Cunha CB, Opal SM. "Middle East respiratory syndrome (MERS): a new zoonotic viral pneumonia." Virulence, vol. 5, no. 6, 2014, pp. 650-4.

Full TextPubMed

DeLeon TT, Chung HH, Opal SM, Dworkin JD. "Mycobacterium avium complex empyema in a patient with interferon gamma autoantibodies." Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health, vol. 73, no. 9 Suppl 1, 2014, pp. 15-7.

PubMed

Opal, Steven. "Number Needed to Treat—To Get Clinicians’ Attention*." Critical care medicine, vol. 42, no. 11, 2014, pp. 2444-2445.

Full TextPubMed

Opal SM. "Significance of sialic acid in Klebsiella pneumoniae K1 capsules." Virulence, vol. 5, no. 6, 2014, pp. 648-9.

Full TextPubMed

Wittebole X, Laterre PF, Opal SM. "Targeting toll-like receptors 4 intracellular domain to prevent ischemic liver disease: an innovative approach or just a futuristic dream?." Critical care medicine, vol. 42, no. 2, 2014, pp. 487-8.

Full TextPubMed

Opal SM, Dellinger RP, Vincent JL, Masur H, Angus DC. "The authors reply." Critical care medicine, vol. 42, no. 12, 2014, pp. e798-9.

Full TextPubMed

Pop-Vicas A, Opal SM. "The clinical impact of multidrug-resistant gram-negative bacilli in the management of septic shock." Virulence, vol. 5, no. 1, 2014, pp. 206-12.

Full TextPubMed

Opal SM. "The current understanding of sepsis and research priorities for the future." Virulence, vol. 5, no. 1, 2014, pp. 1-3.

Full TextPubMed

Opal SM, Fedson DS. "The dysfunctional host response to influenza A H7N9: a potential treatment option?." Critical Care, vol. 18, no. 2, 2014, pp. 135.

Full TextPubMed

Opal SM, Dellinger RP, Vincent JL, Masur H, Angus DC. "The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?*." Critical care medicine, vol. 42, no. 7, 2014, pp. 1714-21.

Full TextPubMed

Ramachandran G, Tulapurkar ME, Harris KM, Arad G, Shirvan A, Shemesh R, Detolla LJ, Benazzi C, Opal SM, Kaempfer R, Cross AS. "A peptide antagonist of CD28 signaling attenuates toxic shock and necrotizing soft-tissue infection induced by Streptococcus pyogenes." The Journal of Infectious Diseases, vol. 207, no. 12, 2013, pp. 1869-77.

Full TextPubMed

Opal SM, Laterre PF, Francois B, LaRosa SP, Angus DC, Mira JP, Wittebole X, Dugernier T, Perrotin D, Tidswell M, Jauregui L, Krell K, Pachl J, Takahashi T, Peckelsen C, Cordasco E, Chang CS, Oeyen S, Aikawa N, Maruyama T, Schein R, Kalil AC, Van Nuffelen M, Lynn M, Rossignol DP, Gogate J, Roberts MB, Wheeler JL, Vincent JL, ACCESS Study Group. "Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial." JAMA, vol. 309, no. 11, 2013, pp. 1154-62.

Full TextPubMed

McCulloh R, Opal SM. "Human recombinant lactoferrin for sepsis: too good to be true?." Critical care medicine, vol. 41, no. 3, 2013, pp. 908-9.

Full TextPubMed

Angione SL, Inde Z, Beck CM, Artenstein AW, Opal SM, Tripathi A. "Microdroplet sandwich real-time rt-PCR for detection of pandemic and seasonal influenza subtypes." PLoS ONE, vol. 8, no. 9, 2013, pp. e73497.

Full TextPubMed

Pop-Vicas A, Opal SM. "Over-distension of the airways by mechanical ventilation in the elderly: adding insult to injury." Critical Care, vol. 17, no. 4, 2013, pp. 165.

Full TextPubMed

Hurley JC, Opal SM. "Prognostic value of endotoxemia in patients with Gram-negative bacteremia is bacterial species dependent." Journal of innate immunity, vol. 5, no. 6, 2013, pp. 555-64.

Full TextPubMed

Opal SM, LaRosa SP. "Recombinant human activated protein C as a therapy for severe sepsis: lessons learned?." Am J Respir Crit Care Med, vol. 187, no. 10, 2013, pp. 1041-3.

Full TextPubMed

Sim BT, Browne SK, Vigliani M, Zachary D, Rosen L, Holland SM, Opal SM. "Recurrent Burkholderia gladioli suppurative lymphadenitis associated with neutralizing anti-IL-12p70 autoantibodies." Journal of clinical immunology, vol. 33, no. 6, 2013, pp. 1057-61.

Full TextPubMed

Artenstein AW, Higgins TL, Opal SM. "Sepsis and scientific revolutions." Critical care medicine, vol. 41, no. 12, 2013, pp. 2770-2.

Full TextPubMed

Vincent JL, Opal SM, Marshall JC, Tracey KJ. "Sepsis definitions - Authors' reply." The Lancet, vol. 381, no. 9885, 2013, pp. 2250.

Full TextPubMed

Vincent JL, Opal SM, Marshall JC, Tracey KJ. "Sepsis definitions: time for change." The Lancet, vol. 381, no. 9868, 2013, pp. 774-5.

Full TextPubMed

Wang J, Tai W, Angione SL, John AR, Opal SM, Artenstein AW, Tripathi A. "Subtyping clinical specimens of influenza A virus by use of a simple method to amplify RNA targets." Journal of clinical microbiology, vol. 51, no. 10, 2013, pp. 3324-30.

Full TextPubMed

Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R, Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. "Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012." Critical care medicine, vol. 41, no. 2, 2013, pp. 580-637.

Full TextPubMed

Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb S, Beale RJ, Vincent JL, Moreno R, Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup. "Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012." Intensive care medicine, vol. 39, no. 2, 2013, pp. 165-228.

Full TextPubMed

Opal SM, Dellinger RP. "The authors reply." Critical care medicine, vol. 41, no. 12, 2013, pp. e488.

Full TextPubMed

Opal SM, Dellinger RP. "The authors reply." Critical care medicine, vol. 41, no. 11, 2013, pp. e386-7.

Full TextPubMed

Fedson DS, Opal SM. "The controversy over H5N1 transmissibility research: an opportunity to define a practical response to a global threat." Human Vaccines & Immunotherapeutics, vol. 9, no. 5, 2013, pp. 977-86.

Full TextPubMed

McCalla SE, Ong C, Sarma A, Opal SM, Artenstein AW, Tripathi A. "A simple method for amplifying RNA targets (SMART)." The Journal of molecular diagnostics : JMD, vol. 14, no. 4, 2012, pp. 328-35.

Full TextPubMed

Opal SM. "ACP Journal Club. Review: Short-course antibiotics in hospital-acquired pneumonia do not affect mortality." Annals of Internal Medicine, vol. 156, no. 6, 2012, pp. JC3-13.

Full TextPubMed

Larosa SP, Opal SM. "Immune aspects of sepsis and hope for new therapeutics." Current Infectious Disease Reports, vol. 14, no. 5, 2012, pp. 474-83.

Full TextPubMed

Ong C, Tai W, Sarma A, Opal SM, Artenstein AW, Tripathi A. "Ligation with nucleic acid sequence-based amplification." The Journal of molecular diagnostics : JMD, vol. 14, no. 3, 2012, pp. 206-13.

Full TextPubMed

Artenstein AW, Opal SM. "Novel approaches to the treatment of systemic anthrax." Clinical Infectious Diseases, vol. 54, no. 8, 2012, pp. 1148-61.

Full TextPubMed

Christaki E, Lazaridis N, Opal SM. "Receptor for advanced glycation end products in bacterial infection: is there a role for immune modulation of receptor for advanced glycation end products in the treatment of sepsis?." Current opinion in infectious diseases, vol. 25, no. 3, 2012, pp. 304-11.

Full TextPubMed

Fedson DS, Opal SM. "Research into transmissibility of influenza A H5N1: a practical response to the controversy." The Lancet infectious diseases, vol. 12, no. 5, 2012, pp. 364-5.

Full TextPubMed

Cohen J, Opal S, Calandra T. "Sepsis studies need new direction." The Lancet infectious diseases, vol. 12, no. 7, 2012, pp. 503-5.

Full TextPubMed

Ismail A, Pop-Vicas A, Opal S. "Spinal epidural abscess." Medicine and health, Rhode Island, vol. 95, no. 1, 2012, pp. 21-2.

PubMed

Tressel SL, Kaneider NC, Kasuda S, Foley C, Koukos G, Austin K, Agarwal A, Covic L, Opal SM, Kuliopulos A. "A matrix metalloprotease-PAR1 system regulates vascular integrity, systemic inflammation and death in sepsis." EMBO molecular medicine, vol. 3, no. 7, 2011, pp. 370-84.

Full TextPubMed

Christaki E, Opal SM, Keith JC Jr, Kessimian N, Palardy JE, Parejo NA, Tan XY, Piche-Nicholas N, Tchistiakova L, Vlasuk GP, Shields KM, Feldman JL, Lavallie ER, Arai M, Mounts W, Pittman DD. "A monoclonal antibody against RAGE alters gene expression and is protective in experimental models of sepsis and pneumococcal pneumonia." Shock, vol. 35, no. 5, 2011, pp. 492-8.

Full TextPubMed

LaRosa SP, Opal SM. "Biomarkers: the future." Critical Care Clinics, vol. 27, no. 2, 2011, pp. 407-19.

Full TextPubMed

Opal SM. "Endotoxemia before and after surgical repair for congenital heart disease." Am J Respir Crit Care Med, vol. 184, no. 11, 2011, pp. 1223-4.

Full TextPubMed

Delsesto D, Opal SM. "Future perspectives on regulating pro-and anti-inflammatory responses in sepsis." Contributions to microbiology, vol. 17, 2011, pp. 137-56.

Full TextPubMed

Opal SM. "Immunologic alterations and the pathogenesis of organ failure in the ICU." Seminars in Respiratory and Critical Care Medicine, vol. 32, no. 5, 2011, pp. 569-80.

Full TextPubMed

Christaki E, Anyfanti P, Opal SM. "Immunomodulatory therapy for sepsis: an update." Expert review of anti-infective therapy, vol. 9, no. 11, 2011, pp. 1013-33.

Full TextPubMed

Kalil AC, LaRosa SP, Gogate J, Lynn M, Opal SM, Eritoran Sepsis Study Group. "Influence of severity of illness on the effects of eritoran tetrasodium (E5564) and on other therapies for severe sepsis." Shock, vol. 36, no. 4, 2011, pp. 327-31.

Full TextPubMed

Opal SM, Lim YP, Cristofaro P, Artenstein AW, Kessimian N, Delsesto D, Parejo N, Palardy JE, Siryaporn E. "Inter-α inhibitor proteins: a novel therapeutic strategy for experimental anthrax infection." Shock, vol. 35, no. 1, 2011, pp. 42-4.

Full TextPubMed

Artenstein AW, Opal SM. "Proprotein convertases in health and disease." New England Journal of Medicine, vol. 365, no. 26, 2011, pp. 2507-18.

Full TextPubMed

Wunderink RG, Laterre PF, Francois B, Perrotin D, Artigas A, Vidal LO, Lobo SM, Juan JS, Hwang SC, Dugernier T, LaRosa S, Wittebole X, Dhainaut JF, Doig C, Mendelson MH, Zwingelstein C, Su G, Opal S, CAPTIVATE Trial Group. "Recombinant tissue factor pathway inhibitor in severe community-acquired pneumonia: a randomized trial." Am J Respir Crit Care Med, vol. 183, no. 11, 2011, pp. 1561-8.

Full TextPubMed

Opal SM. "The evolution of the understanding of sepsis, infection, and the host response: a brief history." Critical care nursing clinics of North America, vol. 23, no. 1, 2011, pp. 1-27.

Full TextPubMed

Kerby MB, Sarma AA, Patel MS, Artenstein AW, Opal SM, Tripathi A. "The PIRO concept: I is for infection." Critical Care, vol. 164, no. 4, 2011, pp. 252-5.

Full TextPubMed

Christ-Crain M, Opal SM. "Clinical review: the role of biomarkers in the diagnosis and management of community-acquired pneumonia." Critical Care, vol. 14, no. 1, 2010, pp. 203.

Full TextPubMed

Al-Qadi MO, Al-Alwan A, Opal SM, Cillley B, Silverblatt FJ. "Community acquired pneumonia." Medicine and health, Rhode Island, vol. 93, no. 7, 2010, pp. 196-200.

PubMed

Gregory SH, Chen WH, Mott S, Palardy JE, Parejo NA, Heninger S, Anderson CA, Artenstein AW, Opal SM, Cross AS. "Detoxified endotoxin vaccine (J5dLPS/OMP) protects mice against lethal respiratory challenge with Francisella tularensis SchuS4." Vaccine, vol. 28, no. 16, 2010, pp. 2908-15.

Full TextPubMed

Opal SM. "Endotoxin desynchronizes biological clocks." Critical care medicine, vol. 38, no. 3, 2010, pp. 977-8.

Full TextPubMed

Opal SM. "Endotoxins and other sepsis triggers." Contributions to nephrology, vol. 167, 2010, pp. 14-24.

Full TextPubMed

Christaki E, Opal SM, Keith JC Jr, Kessinian N, Palardy JE, Parejo NA, Lavallie E, Racie L, Mounts W, Malamas MS, Mewshaw RE, Harris HA, Vlasuk GP. "Estrogen receptor beta agonism increases survival in experimentally induced sepsis and ameliorates the genomic sepsis signature: a pharmacogenomic study." The Journal of Infectious Diseases, vol. 201, no. 8, 2010, pp. 1250-7.

Full TextPubMed

Hotchkiss RS, Opal S. "Immunotherapy for sepsis--a new approach against an ancient foe." New England Journal of Medicine, vol. 363, no. 1, 2010, pp. 87-9.

Full TextPubMed

Opal SM. "New perspectives on immunomodulatory therapy for bacteraemia and sepsis." International journal of antimicrobial agents, vol. 36 Suppl 2, 2010, pp. S70-3.

Full TextPubMed

Tidswell M, Tillis W, Larosa SP, Lynn M, Wittek AE, Kao R, Wheeler J, Gogate J, Opal SM, Eritoran Sepsis Study Group. "Phase 2 trial of eritoran tetrasodium (E5564), a toll-like receptor 4 antagonist, in patients with severe sepsis." Critical care medicine, vol. 38, no. 1, 2010, pp. 72-83.

Full TextPubMed

Vincent JL, Opal SM, Marshall JC. "Ten reasons why we should NOT use severity scores as entry criteria for clinical trials or in our treatment decisions." Critical care medicine, vol. 38, no. 1, 2010, pp. 283-7.

Full TextPubMed

Laterre PF, Opal SM, Abraham E, LaRosa SP, Creasey AA, Xie F, Poole L, Wunderink RG. "A clinical evaluation committee assessment of recombinant human tissue factor pathway inhibitor (tifacogin) in patients with severe community-acquired pneumonia." Critical Care, vol. 13, no. 2, 2009, pp. R36.

Full TextPubMed

Opal SM, Calandra T. "Antibiotic usage and resistance: gaining or losing ground on infections in critically ill patients?." JAMA, vol. 302, no. 21, 2009, pp. 2367-8.

Full TextPubMed

Opal SM. "Coming soon to an ICU near you: severe pandemic influenza in ICU patients in Spain." Critical Care, vol. 13, no. 5, 2009, pp. 196.

Full TextPubMed

Dellinger RP, Tomayko JF, Angus DC, Opal S, Cupo MA, McDermott S, Ducher A, Calandra T, Cohen J, Lipid Infusion and Patient Outcomes in Sepsis (LIPOS) Investigators. "Efficacy and safety of a phospholipid emulsion (GR270773) in Gram-negative severe sepsis: results of a phase II multicenter, randomized, placebo-controlled, dose-finding clinical trial." Critical care medicine, vol. 37, no. 11, 2009, pp. 2929-38.

Full TextPubMed

Cinel I, Opal SM. "Molecular biology of inflammation and sepsis: a primer." Critical care medicine, vol. 37, no. 1, 2009, pp. 291-304.

Full TextPubMed

van der Poll T, Opal SM. "Pathogenesis, treatment, and prevention of pneumococcal pneumonia." The Lancet, vol. 374, no. 9700, 2009, pp. 1543-56.

Full TextPubMed

Opal SM. "Swine flu, pandemics, and critical care." Critical Care, vol. 13, no. 3, 2009, pp. 146.

Full TextPubMed

Opal SM. "The evolution of the understanding of sepsis, infection, and the host response: a brief history." Critical Care Clinics, vol. 25, no. 4, 2009, pp. 637-63, vii.

Full TextPubMed

Opal SM, Patrozou E. "Translational research in the development of novel sepsis therapeutics: logical deductive reasoning or mission impossible?." Critical care medicine, vol. 37, no. 1 Suppl, 2009, pp. S10-5.

Full TextPubMed

Opal SM, LaRosa SP. "Year in review 2008: Critical Care--sepsis." Critical Care, vol. 13, no. 5, 2009, pp. 224.

Full TextPubMed

Asad S, Opal SM. "Bench-to-bedside review: Quorum sensing and the role of cell-to-cell communication during invasive bacterial infection." Critical Care, vol. 12, no. 6, 2008, pp. 236.

Full TextPubMed

Kerby MB, Freeman S, Prachanronarong K, Artenstein AW, Opal SM, Tripathi A. "Direct sequence detection of structured h5 influenza viral RNA." The Journal of molecular diagnostics : JMD, vol. 10, no. 3, 2008, pp. 225-35.

Full TextPubMed

van der Poll T, Opal SM. "Host-pathogen interactions in sepsis." The Lancet infectious diseases, vol. 8, no. 1, 2008, pp. 32-43.

Full TextPubMed

Christaki E, Opal SM. "Is the mortality rate for septic shock really decreasing?." Current Opinion in Critical Care, vol. 14, no. 5, 2008, pp. 580-6.

Full TextPubMed

Patrozou E, Opal S. "Scurvy masquerading as infectious cellulitis [corrected]." Internal medicine journal, vol. 38, no. 6, 2008, pp. 452-3.

Full TextPubMed

LaRosa SP, Opal SM. "Sepsis strategies in development." Clinics in Chest Medicine, vol. 29, no. 4, 2008, pp. 735-47, x-xi.

Full TextPubMed

Carlet J, Cohen J, Calandra T, Opal SM, Masur H. "Sepsis: time to reconsider the concept." Critical care medicine, vol. 36, no. 3, 2008, pp. 964-6.

Full TextPubMed

Aarts MA, Brun-Buisson C, Cook DJ, Kumar A, Opal S, Rocker G, Smith T, Vincent JL, Marshall JC. "Antibiotic management of suspected nosocomial ICU-acquired infection: does prolonged empiric therapy improve outcome?." Intensive care medicine, vol. 33, no. 8, 2007, pp. 1369-78.

Full TextPubMed

Lutterloh EC, Opal SM. "Antibodies against RAGE in sepsis and inflammation: implications for therapy." Expert opinion on pharmacotherapy, vol. 8, no. 9, 2007, pp. 1193-6.

Full TextPubMed

Opal SM. "Can we RESOLVE the treatment of sepsis?." The Lancet, vol. 369, no. 9564, 2007, pp. 803-4.

Full TextPubMed

Opal SM. "Communal living by bacteria and the pathogenesis of urinary tract infections." PLOS Medicine, vol. 4, no. 12, 2007, pp. e349.

Full TextPubMed

Opal SM. "Endotoxin and cytokine detection systems as biomarkers for sepsis-induced renal injury." Contributions to nephrology, vol. 156, 2007, pp. 220-6.

Full TextPubMed

Opal SM, Lim YP, Siryaporn E, Moldawer LL, Pribble JP, Palardy JE, Souza S. "Longitudinal studies of inter-alpha inhibitor proteins in severely septic patients: a potential clinical marker and mediator of severe sepsis." Critical care medicine, vol. 35, no. 2, 2007, pp. 387-92.

Full TextPubMed

Opal SM. "The host response to endotoxin, antilipopolysaccharide strategies, and the management of severe sepsis." International journal of medical microbiology : IJMM, vol. 297, no. 5, 2007, pp. 365-77.

Full TextPubMed

Wiedermann CJ, Keinecke HO, Jürs M, Opal SM. "Baseline severity of sepsis in subjects of the prowess and the Kybersept clinical trials on endogenous anticoagulants." Shock, vol. 25, no. 6, 2006, pp. 657-8.

Full TextPubMed

Hoffmann JN, Wiedermann CJ, Juers M, Ostermann H, Kienast J, Briegel J, Strauss R, Warren BL, Opal SM, KyberSept investigators. "Benefit/risk profile of high-dose antithrombin in patients with severe sepsis treated with and without concomitant heparin." Thrombosis and haemostasis, vol. 95, no. 5, 2006, pp. 850-6.

Full TextPubMed

Levi M, Opal SM. "Coagulation abnormalities in critically ill patients." Critical Care, vol. 10, no. 4, 2006, pp. 222.

Full TextPubMed

LaRosa SP, Opal SM, Utterback B, Yan SC, Helterbrand J, Simpson AJ, Chaowagul W, White NJ, Fisher CJ Jr. "Decreased protein C, protein S, and antithrombin levels are predictive of poor outcome in Gram-negative sepsis caused by Burkholderia pseudomallei." International Journal of Infectious Diseases, vol. 10, no. 1, 2006, pp. 25-31.

Full TextPubMed

Wiedermann CJ, Hoffmann JN, Juers M, Ostermann H, Kienast J, Briegel J, Strauss R, Keinecke HO, Warren BL, Opal SM, KyberSept Investigators. "High-dose antithrombin III in the treatment of severe sepsis in patients with a high risk of death: efficacy and safety." Critical care medicine, vol. 34, no. 2, 2006, pp. 285-92.

Full TextPubMed

Cristofaro P, Opal SM. "Role of Toll-like receptors in infection and immunity: clinical implications." Drugs, vol. 66, no. 1, 2006, pp. 15-29.

Full TextPubMed

Kumar A, Haery C, Paladugu B, Kumar A, Symeoneides S, Taiberg L, Osman J, Trenholme G, Opal SM, Goldfarb R, Parrillo JE. "The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: association with serum lactate and inflammatory cytokine levels." The Journal of Infectious Diseases, vol. 193, no. 2, 2006, pp. 251-8.

Full TextPubMed

Kienast J, Juers M, Wiedermann CJ, Hoffmann JN, Ostermann H, Strauss R, Keinecke HO, Warren BL, Opal SM, KyberSept investigators. "Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation." Journal of thrombosis and haemostasis : JTH, vol. 4, no. 1, 2006, pp. 90-7.

Full TextPubMed

Cristofaro PA, Opal SM, Palardy JE, Parejo NA, Jhung J, Keith JC Jr, Harris HA. "WAY-202196, a selective estrogen receptor-beta agonist, protects against death in experimental septic shock." Critical care medicine, vol. 34, no. 8, 2006, pp. 2188-93.

Full TextPubMed

Opal SM, Palardy JE, Chen WH, Parejo NA, Bhattacharjee AK, Cross AS. "Active immunization with a detoxified endotoxin vaccine protects against lethal polymicrobial sepsis: its use with CpG adjuvant and potential mechanisms." The Journal of Infectious Diseases, vol. 192, no. 12, 2005, pp. 2074-80.

Full TextPubMed

Opal SM. "Concept of PIRO as a new conceptual framework to understand sepsis." Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, vol. 6, no. 3 Suppl, 2005, pp. S55-60.

Full TextPubMed

Artenstein AW, Opal JM, Opal SM, Tramont EC, Peter G, Russell PK. "History of U.S. military contributions to the study of vaccines against infectious diseases." Military Medicine, vol. 170, no. 4 Suppl, 2005, pp. 3-11.

Full TextPubMed

Girard TD, Opal SM, Ely EW. "Insights into severe sepsis in older patients: from epidemiology to evidence-based management." Clinical Infectious Diseases, vol. 40, no. 5, 2005, pp. 719-27.

Full TextPubMed

Opal SM, Artenstein AW, Cristofaro PA, Jhung JW, Palardy JE, Parejo NA, Lim YP. "Inter-alpha-inhibitor proteins are endogenous furin inhibitors and provide protection against experimental anthrax intoxication." Infection and Immunity, vol. 73, no. 8, 2005, pp. 5101-5.

Full TextPubMed

Thompson AE, Marshall JC, Opal SM. "Intraabdominal infections in infants and children: descriptions and definitions." Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, vol. 6, no. 3 Suppl, 2005, pp. S30-5.

Full TextPubMed

Marshall JC, Deitch E, Moldawer LL, Opal S, Redl H, van der Poll T. "Preclinical models of shock and sepsis: what can they tell us?." Shock, vol. 24 Suppl 1, 2005, pp. 1-6.

PubMed

Opal SM, Palardy JE, Cristofaro P, Parejo N, Jhung JW, Keith JC Jr, Chippari S, Caggiano TJ, Steffan RJ, Chadwick CC, Harnish DC. "The activity of pathway-selective estrogen receptor ligands in experimental septic shock." Shock, vol. 24, no. 6, 2005, pp. 535-40.

Full TextPubMed

Opal SM, Girard TD, Ely EW. "The immunopathogenesis of sepsis in elderly patients." Clinical Infectious Diseases, vol. 41 Suppl 7, 2005, pp. S504-12.

Full TextPubMed

Opal SM, Cross AS. "The use of immunocompromised animals as models for human septic shock." Shock, vol. 24 Suppl 1, 2005, pp. 64-70.

PubMed

LaRosa SP, Opal SM. "Tissue factor pathway inhibitor and antithrombin trial results." Critical Care Clinics, vol. 21, no. 3, 2005, pp. 433-48.

Full TextPubMed

Glück T, Opal SM. "Advances in sepsis therapy." Drugs, vol. 64, no. 8, 2004, pp. 837-59.

Full TextPubMed

Reinhart K, Glück T, Ligtenberg J, Tschaikowsky K, Bruining A, Bakker J, Opal S, Moldawer LL, Axtelle T, Turner T, Souza S, Pribble J. "CD14 receptor occupancy in severe sepsis: results of a phase I clinical trial with a recombinant chimeric CD14 monoclonal antibody (IC14)." Critical care medicine, vol. 32, no. 5, 2004, pp. 1100-8.

Full TextPubMed

Artenstein AW, Opal SM, Cristofaro P, Palardy JE, Parejo NA, Green MD, Jhung JW. "Chloroquine enhances survival in Bacillus anthracis intoxication." The Journal of Infectious Diseases, vol. 190, no. 9, 2004, pp. 1655-60.

Full TextPubMed

Amaral A, Opal SM, Vincent JL. "Coagulation in sepsis." Intensive care medicine, vol. 30, no. 6, 2004, pp. 1032-40.

Full TextPubMed

Cross AS, Opal S, Cook P, Drabick J, Bhattacharjee A. "Development of an anti-core lipopolysaccharide vaccine for the prevention and treatment of sepsis." Vaccine, vol. 22, no. 7, 2004, pp. 812-7.

Full TextPubMed

Marshall JC, Foster D, Vincent JL, Cook DJ, Cohen J, Dellinger RP, Opal S, Abraham E, Brett SJ, Smith T, Mehta S, Derzko A, Romaschin A, MEDIC study. "Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study." The Journal of Infectious Diseases, vol. 190, no. 3, 2004, pp. 527-34.

Full TextPubMed

Cohen J, Cristofaro P, Carlet J, Opal S. "New method of classifying infections in critically ill patients." Critical care medicine, vol. 32, no. 7, 2004, pp. 1510-26.

Full TextPubMed

Opal S, Laterre PF, Abraham E, Francois B, Wittebole X, Lowry S, Dhainaut JF, Warren B, Dugernier T, Lopez A, Sanchez M, Demeyer I, Jauregui L, Lorente JA, McGee W, Reinhart K, Kljucar S, Souza S, Pribble J, Controlled Mortality Trial of Platelet-Activating Factor Acetylhydrolase in Severe Sepsis Investigators. "Recombinant human platelet-activating factor acetylhydrolase for treatment of severe sepsis: results of a phase III, multicenter, randomized, double-blind, placebo-controlled, clinical trial." Critical care medicine, vol. 32, no. 2, 2004, pp. 332-41.

Full TextPubMed

Gea-Banacloche JC, Opal SM, Jorgensen J, Carcillo JA, Sepkowitz KA, Cordonnier C. "Sepsis associated with immunosuppressive medications: an evidence-based review." Critical care medicine, vol. 32, no. 11 Suppl, 2004, pp. S578-90.

Full TextPubMed

Opal SM. "The nexus between systemic inflammation and disordered coagulation in sepsis." Journal of Endotoxin Research, vol. 10, no. 2, 2004, pp. 125-9.

Full TextPubMed

Opal SM. "Unintended bias, clinical trial results, and the heparin post hoc crossover fallacy." Critical care medicine, vol. 32, no. 3, 2004, pp. 874-5.

Full TextPubMed

Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G, International Sepsis Definitions Conference. "2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference." Intensive care medicine, vol. 29, no. 4, 2003, pp. 530-8.

Full TextPubMed

Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G, SCCM/ESICM/ACCP/ATS/SIS. "2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference." Critical care medicine, vol. 31, no. 4, 2003, pp. 1250-6.

Full TextPubMed

Opal S. "[Severe sepsis: perspectives]." Annales francaises d'anesthesie et de reanimation, vol. 22 Spec No 1, 2003, pp. 31-3.

PubMed

Opal S. "[The FDA's questions]." Annales francaises d'anesthesie et de reanimation, vol. 22 Spec No 1, 2003, pp. 20-2.

PubMed

Cross AS, Opal SM. "A new paradigm for the treatment of sepsis: is it time to consider combination therapy?." Annals of Internal Medicine, vol. 138, no. 6, 2003, pp. 502-5.

Full TextPubMed

Opal SM, Esmon CT. "Bench-to-bedside review: functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis." Critical Care, vol. 7, no. 1, 2003, pp. 23-38.

Full TextPubMed

Opal SM. "Clinical trial design and outcomes in patients with severe sepsis." Shock, vol. 20, no. 4, 2003, pp. 295-302.

Full TextPubMed

Lim YP, Bendelja K, Opal SM, Siryaporn E, Hixson DC, Palardy JE. "Correlation between mortality and the levels of inter-alpha inhibitors in the plasma of patients with severe sepsis." The Journal of Infectious Diseases, vol. 188, no. 6, 2003, pp. 919-26.

Full TextPubMed

Opal SM. "Corticosteroids for patients with septic shock." JAMA, vol. 289, no. 1, 2003, pp. 41-2; author reply 43-4.

PubMed

Opal SM, Palardy JE, Parejo N, Jasman RL. "Effect of anti-CD14 monoclonal antibody on clearance of Escherichia coli bacteremia and endotoxemia." Critical care medicine, vol. 31, no. 3, 2003, pp. 929-32.

Full TextPubMed

Abraham E, Reinhart K, Opal S, Demeyer I, Doig C, Rodriguez AL, Beale R, Svoboda P, Laterre PF, Simon S, Light B, Spapen H, Stone J, Seibert A, Peckelsen C, De Deyne C, Postier R, Pettilä V, Artigas A, Percell SR, Shu V, Zwingelstein C, Tobias J, Poole L, Stolzenbach JC, Creasey AA, OPTIMIST Trial Study Group. "Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial." JAMA, vol. 290, no. 2, 2003, pp. 238-47.

Full TextPubMed

Opal SM, Glück T. "Endotoxin as a drug target." Critical care medicine, vol. 31, no. 1 Suppl, 2003, pp. S57-64.

Full TextPubMed

Opal SM. "Interactions between coagulation and inflammation." Scandinavian journal of infectious diseases, vol. 35, no. 9, 2003, pp. 545-54.

Full TextPubMed

Opal SM, Keith JC Jr, Jhung J, Palardy JE, Parejo N, Marchese E, Maganti V. "Orally administered recombinant human interleukin-11 is protective in experimental neutropenic sepsis." The Journal of Infectious Diseases, vol. 187, no. 1, 2003, pp. 70-6.

Full TextPubMed

Cross AS, Opal SM, Palardy JE, Drabick JJ, Warren HS, Huber C, Cook P, Bhattacharjee AK. "Phase I study of detoxified Escherichia coli J5 lipopolysaccharide (J5dLPS)/group B meningococcal outer membrane protein (OMP) complex vaccine in human subjects." Vaccine, vol. 21, no. 31, 2003, pp. 4576-87.

Full TextPubMed

Schuster DP, Metzler M, Opal S, Lowry S, Balk R, Abraham E, Levy H, Slotman G, Coyne E, Souza S, Pribble J, Pafase ARDS Prevention Study Group. "Recombinant platelet-activating factor acetylhydrolase to prevent acute respiratory distress syndrome and mortality in severe sepsis: Phase IIb, multicenter, randomized, placebo-controlled, clinical trial." Critical care medicine, vol. 31, no. 6, 2003, pp. 1612-9.

Full TextPubMed

Opal SM. "Severe sepsis and septic shock: defining the clinical problem." Scandinavian journal of infectious diseases, vol. 35, no. 9, 2003, pp. 529-34.

Full TextPubMed

Opal SM, Garber GE, LaRosa SP, Maki DG, Freebairn RC, Kinasewitz GT, Dhainaut JF, Yan SB, Williams MD, Graham DE, Nelson DR, Levy H, Bernard GR. "Systemic host responses in severe sepsis analyzed by causative microorganism and treatment effects of drotrecogin alfa (activated)." Clinical Infectious Diseases, vol. 37, no. 1, 2003, pp. 50-8.

Full TextPubMed

Cristofaro P, Opal SM. "The Toll-like receptors and their role in septic shock." Expert Opinion on Therapeutic Targets, vol. 7, no. 5, 2003, pp. 603-12.

Full TextPubMed

Opal SM, Kessler CM, Roemisch J, Knaub S. "Antithrombin, heparin, and heparan sulfate." Critical care medicine, vol. 30, no. 5 Suppl, 2002, pp. S325-31.

Full TextPubMed

Opal SM, Huber CE. "Bench-to-bedside review: Toll-like receptors and their role in septic shock." Critical Care, vol. 6, no. 2, 2002, pp. 125-36.

Full TextPubMed

Artenstein AW, Neill MA, Opal SM. "Bioterrorism and physicians." Annals of Internal Medicine, vol. 137, no. 7, 2002, pp. 626.

PubMed

Artenstein AW, Neill MA, Opal SM. "Bioterrorism and physicians." Medicine and health, Rhode Island, vol. 85, no. 2, 2002, pp. 74-6.

PubMed

Opal SM. "Insights into the immune dysfunction associated with thermal injury." Critical care medicine, vol. 30, no. 7, 2002, pp. 1651-2.

Full TextPubMed

Rublee D, Opal SM, Schramm W, Keinecke HO, Knaub S. "Quality of life effects of antithrombin III in sepsis survivors: results from the KyberSept trial [ISRCTN22931023]." Critical Care, vol. 6, no. 4, 2002, pp. 349-56.

PubMed

Manalo R, Mirza H, Opal S. "Streptococcus pyogenes tuboovarian abscess: a potential sexually transmitted disease?." Sexually Transmitted Diseases, vol. 29, no. 10, 2002, pp. 606-7.

Full TextPubMed

Opal SM. "The clinical relevance of endotoxin in human sepsis: a critical analysis." Journal of Endotoxin Research, vol. 8, no. 6, 2002, pp. 473-6.

Full TextPubMed

Cross AS, Opal SM, Warren HS, Palardy JE, Glaser K, Parejo NA, Bhattacharjee AK. "Active immunization with a detoxified Escherichia coli J5 lipopolysaccharide group B meningococcal outer membrane protein complex vaccine protects animals from experimental sepsis." The Journal of Infectious Diseases, vol. 183, no. 7, 2001, pp. 1079-86.

Full TextPubMed

Warren BL, Eid A, Singer P, Pillay SS, Carl P, Novak I, Chalupa P, Atherstone A, Pénzes I, Kübler A, Knaub S, Keinecke HO, Heinrichs H, Schindel F, Juers M, Bone RC, Opal SM, KyberSept Trial Study Group. "Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial." JAMA, vol. 286, no. 15, 2001, pp. 1869-78.

Full TextPubMed

Opal SM. "Clinical impact of novel anticoagulation strategies in sepsis." Current Opinion in Critical Care, vol. 7, no. 5, 2001, pp. 347-53.

Full TextPubMed

Opal SM, Sypek JP, Keith JC Jr, Schaub RG, Palardy JE, Parejo NA. "Evaluation of the safety of recombinant P-selectin glycoprotein ligand-immunoglobulin G fusion protein in experimental models of localized and systemic infection." Shock, vol. 15, no. 4, 2001, pp. 285-90.

Full TextPubMed

Opal SM, Palardy JE, Parejo N, Morrison DC. "Lipopolyamines as a therapeutic strategy in experimental Gram-negative bacterial sepsis." Journal of Endotoxin Research, vol. 7, no. 1, 2001, pp. 35-8.

Full TextPubMed

Cohen J, Guyatt G, Bernard GR, Calandra T, Cook D, Elbourne D, Marshall J, Nunn A, Opal S, UK Medical Research Council International Working Party. "New strategies for clinical trials in patients with sepsis and septic shock." Critical care medicine, vol. 29, no. 4, 2001, pp. 880-6.

Full TextPubMed

Opal SM. "Protein C levels in severe sepsis." Chest, vol. 120, no. 3, 2001, pp. 699-701.

Full TextPubMed

Florquin S, van den Berg JG, Olszyna DP, Claessen N, Opal SM, Weening JJ, van der Poll T. "Release of urokinase plasminogen activator receptor during urosepsis and endotoxemia." Kidney International, vol. 59, no. 6, 2001, pp. 2054-61.

Full TextPubMed

Opal SM, Palardy JE, Parejo NA, Creasey AA. "The activity of tissue factor pathway inhibitor in experimental models of superantigen-induced shock and polymicrobial intra-abdominal sepsis." Critical care medicine, vol. 29, no. 1, 2001, pp. 13-7.

Full TextPubMed

Luchi M, Morrison DC, Opal S, Yoneda K, Slotman G, Chambers H, Wiesenfeld H, Lemke J, Ryan JL, Horn D. "A comparative trial of imipenem versus ceftazidime in the release of endotoxin and cytokine generation in patients with gram-negative urosepsis. Urosepsis Study Group." Journal of Endotoxin Research, vol. 6, no. 1, 2000, pp. 25-31.

Full TextPubMed

Opal SM, DePalo VA. "Anti-inflammatory cytokines." Chest, vol. 117, no. 4, 2000, pp. 1162-72.

Full TextPubMed

Olszyna DP, Opal SM, Prins JM, Horn DL, Speelman P, van Deventer SJ, van der Poll T. "Chemotactic activity of CXC chemokines interleukin-8, growth-related oncogene-alpha, and epithelial cell-derived neutrophil-activating protein-78 in urine of patients with urosepsis." The Journal of Infectious Diseases, vol. 182, no. 6, 2000, pp. 1731-7.

Full TextPubMed

Abraham E, Matthay MA, Dinarello CA, Vincent JL, Cohen J, Opal SM, Glauser M, Parsons P, Fisher CJ Jr, Repine JE. "Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation." Critical care medicine, vol. 28, no. 1, 2000, pp. 232-5.

Full TextPubMed

Glück T, Opal S, Alattar-Mantis J, Weitzel T, Lode H, Schölmerich J. "Differences between American and German medical students and physicians in knowledge of infectious diseases." European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, vol. 19, no. 11, 2000, pp. 868-70.

Full TextPubMed

Simpson AJ, Opal SM, Angus BJ, Prins JM, Palardy JE, Parejo NA, Chaowagul W, White NJ. "Differential antibiotic-induced endotoxin release in severe melioidosis." The Journal of Infectious Diseases, vol. 181, no. 3, 2000, pp. 1014-9.

Full TextPubMed

Opal SM. "Hemofiltration-absorption systems for the treatment of experimental sepsis: is it possible to remove the "evil humors" responsible for septic shock?." Critical care medicine, vol. 28, no. 5, 2000, pp. 1681-2.

Full TextPubMed

Opal SM. "Phylogenetic and functional relationships between coagulation and the innate immune response." Critical care medicine, vol. 28, no. 9 Suppl, 2000, pp. S77-80.

Full TextPubMed

Opal SM, Keith JC, Palardy JE, Parejo N. "Recombinant human interleukin-11 has anti-inflammatory actions yet does not exacerbate systemic Listeria infection." The Journal of Infectious Diseases, vol. 181, no. 2, 2000, pp. 754-6.

Full TextPubMed

Opal S, Thijs L, Cavaillon JM, Cohen J, Fourrier F. "Roundtable I: relationships between coagulation and inflammatory processes." Critical care medicine, vol. 28, no. 9 Suppl, 2000, pp. S81-2.

Full TextPubMed

Opal SM, Huber CE. "The role of interleukin-10 in critical illness." Current opinion in infectious diseases, vol. 13, no. 3, 2000, pp. 221-226.

Full TextPubMed

Opal SM. "Therapeutic rationale for antithrombin III in sepsis." Critical care medicine, vol. 28, no. 9 Suppl, 2000, pp. S34-7.

Full TextPubMed

Horn DL, Morrison DC, Opal SM, Silverstein R, Visvanathan K, Zabriskie JB. "What are the microbial components implicated in the pathogenesis of sepsis? Report on a symposium." Clinical Infectious Diseases, vol. 31, no. 4, 2000, pp. 851-8.

Full TextPubMed

Opal SM, Jhung JW, Keith JC Jr, Goldman SJ, Palardy JE, Parejo NA. "Additive effects of human recombinant interleukin-11 and granulocyte colony-stimulating factor in experimental gram-negative sepsis." Blood, vol. 93, no. 10, 1999, pp. 3467-72.

PubMed

Opal SM, Cohen J. "Clinical gram-positive sepsis: does it fundamentally differ from gram-negative bacterial sepsis?." Critical care medicine, vol. 27, no. 8, 1999, pp. 1608-16.

Full TextPubMed

Opal SM, Cross AS. "Clinical trials for severe sepsis. Past failures, and future hopes." Infectious disease clinics of North America, vol. 13, no. 2, 1999, pp. 285-97, vii.

Full TextPubMed

Cross AS, Opal SM, Bhattacharjee AK, Donta ST, Peduzzi PN, Fürer E, Que JU, Cryz SJ. "Immunotherapy of sepsis: flawed concept or faulty implementation?." Vaccine, vol. 17 Suppl 2, 1999, pp. S13-21.

PubMed

Opal SM, Scannon PJ, Vincent JL, White M, Carroll SF, Palardy JE, Parejo NA, Pribble JP, Lemke JH. "Relationship between plasma levels of lipopolysaccharide (LPS) and LPS-binding protein in patients with severe sepsis and septic shock." The Journal of Infectious Diseases, vol. 180, no. 5, 1999, pp. 1584-9.

Full TextPubMed

Opal SM. "Selenium replacement in severe systemic inflammatory response syndrome." Critical care medicine, vol. 27, no. 9, 1999, pp. 2042-3.

Full TextPubMed

Opal SM. "Tumor necrosis factor receptor expression on inflammatory cells in sepsis." Critical care medicine, vol. 27, no. 2, 1999, pp. 240-1.

Full TextPubMed

Opal SM, Yu RL Jr. "Antiendotoxin strategies for the prevention and treatment of septic shock. New approaches and future directions." Drugs, vol. 55, no. 4, 1998, pp. 497-508.

Full TextPubMed

Opal SM, Wherry JC, Grint P. "Interleukin-10: potential benefits and possible risks in clinical infectious diseases." Clinical Infectious Diseases, vol. 27, no. 6, 1998, pp. 1497-507.

Full TextPubMed

Opal SM, Jhung JW, Keith JC Jr, Palardy JE, Parejo NA, Young LD, Bhattacharjee A. "Recombinant human interleukin-11 in experimental Pseudomonas aeruginosa sepsis in immunocompromised animals." The Journal of Infectious Diseases, vol. 178, no. 4, 1998, pp. 1205-8.

PubMed

Opal SM. "The uncertain value of the definition for SIRS. Systemic inflammatory response syndrome." Chest, vol. 113, no. 6, 1998, pp. 1442-3.

Full TextPubMed

Horn DL, Zabriskie JB, Austrian R, Cleary PP, Ferretti JJ, Fischetti VA, Gotschlich E, Kaplan EL, McCarty M, Opal SM, Roberts RB, Tomasz A, Wachtfogel Y. "Why have group A streptococci remained susceptible to penicillin? Report on a symposium." Clinical Infectious Diseases, vol. 26, no. 6, 1998, pp. 1341-5.

Full TextPubMed

Ruzek MC, Miller AH, Opal SM, Pearce BD, Biron CA. "Characterization of early cytokine responses and an interleukin (IL)-6-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection." Journal of Experimental Medicine, vol. 185, no. 7, 1997, pp. 1185-92.

Full TextPubMed

Opal SM, Fisher CJ Jr, Dhainaut JF, Vincent JL, Brase R, Lowry SF, Sadoff JC, Slotman GJ, Levy H, Balk RA, Shelly MP, Pribble JP, LaBrecque JF, Lookabaugh J, Donovan H, Dubin H, Baughman R, Norman J, DeMaria E, Matzel K, Abraham E, Seneff M. "Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group." Critical care medicine, vol. 25, no. 7, 1997, pp. 1115-24.

Full TextPubMed

Orange JS, Salazar-Mather TP, Opal SM, Biron CA. "Mechanisms for virus-induced liver disease: tumor necrosis factor-mediated pathology independent of natural killer and T cells during murine cytomegalovirus infection." Journal of Virology, vol. 71, no. 12, 1997, pp. 9248-58.

PubMed

Bhattacharjee AK, Opal SM, Taylor R, Naso R, Semenuk M, Zollinger WD, Moran EE, Young L, Hammack C, Sadoff JC, Cross AS. "A noncovalent complex vaccine prepared with detoxified Escherichia coli J5 (Rc chemotype) lipopolysaccharide and Neisseria meningitidis Group B outer membrane protein produces protective antibodies against gram-negative bacteremia." The Journal of Infectious Diseases, vol. 173, no. 5, 1996, pp. 1157-63.

Full TextPubMed

Horn DL, Opal SM, Lomastro E. "Antibiotics, cytokines, and endotoxin: a complex and evolving relationship in gram-negative sepsis." Scandinavian journal of infectious diseases. Supplementum, vol. 101, 1996, pp. 9-13.

PubMed

Opal SM. "Infectious disease challenges in the 1990's." Medicine and health, Rhode Island, vol. 79, no. 3, 1996, pp. 100-9.

PubMed

Opal SM, Cross AS, Jhung JW, Young LD, Palardy JE, Parejo NA, Donsky C. "Potential hazards of combination immunotherapy in the treatment of experimental septic shock." The Journal of Infectious Diseases, vol. 173, no. 6, 1996, pp. 1415-21.

Full TextPubMed

Fisher CJ Jr, Agosti JM, Opal SM, Lowry SF, Balk RA, Sadoff JC, Abraham E, Schein RM, Benjamin E. "Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The Soluble TNF Receptor Sepsis Study Group." New England Journal of Medicine, vol. 334, no. 26, 1996, pp. 1697-702.

Full TextPubMed

Opal SM, Palardy JE, Jhung JW, Donsky C, Romulo RL, Parejo N, Marra MN. "Activity of lipopolysaccharide-binding protein-bactericidal/permeability-increasing protein fusion peptide in an experimental model of Pseudomonas sepsis." Antimicrobial Agents and Chemotherapy, vol. 39, no. 12, 1995, pp. 2813-5.

Full TextPubMed

Coronado BE, Opal SM, Yoburn DC. "Antibiotic-induced D-lactic acidosis." Annals of Internal Medicine, vol. 122, no. 11, 1995, pp. 839-42.

Full TextPubMed

Rice SK, Heinl RE, Thornton LL, Opal SM. "Clinical characteristics, management strategies, and cost implications of a statewide outbreak of enterovirus meningitis." Clinical Infectious Diseases, vol. 20, no. 4, 1995, pp. 931-7.

Full TextPubMed

Meyerhoff A, Renzi RM, Wehbe T, Opal SM. "Fatal clostridial sepsis in a previously healthy woman." Clinical Infectious Diseases, vol. 20, no. 4, 1995, pp. 1066-7.

Full TextPubMed

Orange JS, Salazar-Mather TP, Opal SM, Spencer RL, Miller AH, McEwen BS, Biron CA. "Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids." Journal of Experimental Medicine, vol. 181, no. 3, 1995, pp. 901-14.

Full TextPubMed

Bhattacharjee AK, Opal SM, Palardy JE, Drabick JJ, Collins H, Taylor R, Cotton A, Cross AS. "Affinity-purified Escherichia coli J5 lipopolysaccharide-specific IgG protects neutropenic rats against gram-negative bacterial sepsis." The Journal of Infectious Diseases, vol. 170, no. 3, 1994, pp. 622-9.

Full TextPubMed

Pololi LH, Coletta EM, Kern DG, Davis S, Kiessling LS, Garber CE, Entin EJ, Opal SM, Rakowski W. "Developing a competency-based preventive medicine curriculum for medical schools." American Journal of Preventive Medicine, vol. 10, no. 4, 1994, pp. 240-4.

PubMed

Suitters AJ, Foulkes R, Opal SM, Palardy JE, Emtage JS, Rolfe M, Stephens S, Morgan A, Holt AR, Chaplin LC. "Differential effect of isotype on efficacy of anti-tumor necrosis factor alpha chimeric antibodies in experimental septic shock." Journal of Experimental Medicine, vol. 179, no. 3, 1994, pp. 849-56.

Full TextPubMed

Fisher CJ Jr, Marra MN, Palardy JE, Marchbanks CR, Scott RW, Opal SM. "Human neutrophil bactericidal/permeability-increasing protein reduces mortality rate from endotoxin challenge: a placebo-controlled study." Critical care medicine, vol. 22, no. 4, 1994, pp. 553-8.

Full TextPubMed

Fisher CJ Jr, Slotman GJ, Opal SM, Pribble JP, Bone RC, Emmanuel G, Ng D, Bloedow DC, Catalano MA, IL-1RA Sepsis Syndrome Study Group. "Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial." Critical care medicine, vol. 22, no. 1, 1994, pp. 12-21.

Full TextPubMed

Horn DL, Hewlett D Jr, Alfalla C, Peterson S, Opal SM. "Limited tolerance of ofloxacin and pyrazinamide prophylaxis against tuberculosis." New England Journal of Medicine, vol. 330, no. 17, 1994, pp. 1241.

Full TextPubMed

Boyce JM, Opal SM, Chow JW, Zervos MJ, Potter-Bynoe G, Sherman CB, Romulo RL, Fortna S, Medeiros AA. "Outbreak of multidrug-resistant Enterococcus faecium with transferable vanB class vancomycin resistance." Journal of clinical microbiology, vol. 32, no. 5, 1994, pp. 1148-53.

PubMed

Fisher CJ Jr, Dhainaut JF, Opal SM, Pribble JP, Balk RA, Slotman GJ, Iberti TJ, Rackow EC, Shapiro MJ, Greenman RL. "Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome. Results from a randomized, double-blind, placebo-controlled trial. Phase III rhIL-1ra Sepsis Syndrome Study Group." JAMA, vol. 271, no. 23, 1994, pp. 1836-43.

Full TextPubMed

Opal SM, Palardy JE, Marra MN, Fisher CJ Jr, McKelligon BM, Scott RW. "Relative concentrations of endotoxin-binding proteins in body fluids during infection." The Lancet, vol. 344, no. 8920, 1994, pp. 429-31.

Full TextPubMed

Sours: https://vivo.brown.edu/display/sopalmd

Care opal gene skin

I started Opal Artistry with two main goals: to celebrate natural beauty, and to take inspiration from the multifaceted meaning of opals and their power to stimulate originality and creativity.

I have been providing hair styling and makeup artistry for special events while crafting a successful business as a color and highlight specialist for more than 10 years. What I love most is connecting with all types of wonderful people and personalities while simultaneously creating looks ranging from natural and understated to edgy and glamorous.

I started my beauty career at the Gene Juarez Academy, and the GJ advanced training academy. It was here that I trained with some of the leading professionals in the industry. Next, I followed my love of makeup to theGlam Lab Academy, where I became a certified makeup artist. In 10+ years of professional makeup and hair experience, my work has garnered national attention, including makeup services for the Why Don’t We -featuring Macklemore music video “I Don’t Belong in This Club” and a spotlight in Wandering Weddings Magazine. 

My goal? Make everyone who sits in my chair feel confident and beautiful in their own skin, while also passing on application tips and education to help you understand how you can give yourself a professional level glow-up at home. I tailor every beauty experience based on your needs, desires, and vision, so each and every client walks away looking and feeling like absolute magic.

Sours: https://www.opalartistry.me/about
Benefits of the Clarisonic Opal

A historical overview of bacteriophage therapy as an alternative to antibiotics for the treatment of bacterial pathogens

1. Sulakvelidze A. Bacteriophage: A new journal for the most ubiquitous organisms on Earth. Bacteriophage. 2011;1:1–2. doi: 10.4161/bact.1.1.15030.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

2. Weinbauer MG. Ecology of prokaryotic viruses. FEMS Microbiol Rev. 2004;28:127–81. doi: 10.1016/j.femsre.2003.08.001. [PubMed] [CrossRef] [Google Scholar]

3. Hanlon GW. Bacteriophages: an appraisal of their role in the treatment of bacterial infections. Int J Antimicrob Agents. 2007;30:118–28. doi: 10.1016/j.ijantimicag.2007.04.006. [PubMed] [CrossRef] [Google Scholar]

4. d’Herelle F. Bacteriophage as a treatment in acute medical and surgical infections. Bull N Y Acad Med. 1931;7:329–48.[PMC free article] [PubMed] [Google Scholar]

5. Abedon ST, Kuhl SJ, Blasdel BG, Kutter EM. Phage treatment of human infections. Bacteriophage. 2011;1:66–85. doi: 10.4161/bact.1.2.15845.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

6. Chanishvili N. Phage therapy--history from Twort and d’Herelle through Soviet experience to current approaches. Adv Virus Res. 2012;83:3–40. doi: 10.1016/B978-0-12-394438-2.00001-3. [PubMed] [CrossRef] [Google Scholar]

7. Eaton MD, Stanhope BJ. Bacteriophage therapy: review of the principle and results of the use of bacteriophage in the treatment of infection (I) J Am Med Assoc. 1934;103:1769–76. doi: 10.1001/jama.1934.72750490003007. [CrossRef] [Google Scholar]

8. Eaton MD, Stanhope BJ. Bacteriophage therapy: review of the principle and results of the use of bacteriophage in the treatment of infection (II) J Am Med Assoc. 1934;103:1847–53. doi: 10.1001/jama.1934.72750500003009. [CrossRef] [Google Scholar]

9. Eaton MD, Stanhope BJ. Bacteriophage therapy: review of the principle and results of the use of bacteriophage in the treatment of infection (III) J Am Med Assoc. 1934;103:1934–9. doi: 10.1001/jama.1934.72750510005009. [CrossRef] [Google Scholar]

10. Hankin EH. L’action bactericide des eaux de la Jumna et du Gange sur le vibrion du cholera. Ann Inst Pasteur (Paris) 1896;10:511–23.[Google Scholar]

11. Twort FW. An investigation on the nature of ultra-microscopic viruses. Lancet. 1915;186:1241–3. doi: 10.1016/S0140-6736(01)20383-3. [CrossRef] [Google Scholar]

12. d’Herelle F. Sur un microbe invisible antagoniste des bacilles dysentériques. C R Acad Sci Paris. 1917;165:173–5.[Google Scholar]

13. Bordet J, Ciuca M. Remarques sur l’historique des recherches concernant la lyse microbienne transmissible. C R Soc Biol. 1921;84:745–7.[Google Scholar]

14. Duckworth DH. “Who discovered bacteriophage?” Bacteriol Rev. 1976;40:793–802.[PMC free article] [PubMed] [Google Scholar]

15. Summers WC. In the beginning… Bacteriophage. 2011;1:50–1. doi: 10.4161/bact.1.1.14070.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

16. Bruynoghe R, Maisin J. Essais de thérapeutique au moyen du bacteriophage du Staphylocoque. Compt Rend Soc Biol. 1921;85:1120–1.[Google Scholar]

17. Northrop JH. Concentration and purification of bacteriophage. J Gen Physiol. 1938;21:335–66. doi: 10.1085/jgp.21.3.335.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

18. Wollman E. Bacteriophage et processus similaire: Hérédité ou Infection? Bull Inst Pasteur Paris. 1928;26:1–14.[Google Scholar]

19. Muller HJ. Variation due to change in the individual gene. Am Nat. 1922;56:32–50. doi: 10.1086/279846. [CrossRef] [Google Scholar]

20. Bordet J. Le problème de l’autolyse microbienne transmissible ou du bacteriophage. Ann Inst Pasteur (Paris) 1925;39:711–63.[Google Scholar]

21. Sankaran N. The bacteriophage, its role in immunology: how Macfarlane Burnet’s phage research shaped his scientific life. Studies in History and Phylosophy of Biological and Biomedical Sciences. 2010;41:367–75. doi: 10.1016/j.shpsc.2010.10.012. [PubMed] [CrossRef] [Google Scholar]

22. Burnet FM. The serological classification of Coli-Dysentery phages. J Pathol Bacteriol. 1933;36:307–18. doi: 10.1002/path.1700360212. [CrossRef] [Google Scholar]

23. Pennazio S. The origin of phage virology. Riv Biol. 2006;99:103–29. [PubMed] [Google Scholar]

24. Schlesinger M. Zur frage der chemischen zusammensetzung des bakteriophagen. Biochem Z. 1934;273:306–11.[Google Scholar]

25. Ruska H. Die Sichtbarmachung der bakteriophagen Lyse im Übermikroskop. Naturwissenschaften. 1940;28:45–6. doi: 10.1007/BF01486931. [CrossRef] [Google Scholar]

26. Kruger DH, Schneck P, Gelderblom HR. Helmut Ruska and the visualisation of viruses. Lancet. 2000;355:1713–7. doi: 10.1016/S0140-6736(00)02250-9. [PubMed] [CrossRef] [Google Scholar]

27. Luria SE, Anderson TF. The identification and characterization of bacteriophages with the electron microscope. Proc Natl Acad Sci U S A. 1942;28:127–130.1. doi: 10.1073/pnas.28.4.127.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

28. Luria SE, Delbrück M, Anderson TF. Electron Microscope Studies of Bacterial Viruses. J Bacteriol. 1943;46:57–77.[PMC free article] [PubMed] [Google Scholar]

29. Smith HW, Huggins MB. Successful treatment of experimental Escherichia coli infections in mice using phage: its general superiority over antibiotics. J Gen Microbiol. 1982;128:307–18. [PubMed] [Google Scholar]

30. Smith HW, Huggins MB. Effectiveness of phages in treating experimental Escherichia coli diarrhoea in calves, piglets and lambs. J Gen Microbiol. 1983;129:2659–75. [PubMed] [Google Scholar]

31. Rhoads DD, Wolcott RD, Kuskowski MA, Wolcott BM, Ward LS, Sulakvelidze A. Bacteriophage therapy of venous leg ulcers in humans: results of a phase I safety trial. J Wound Care. 2009;18:237–8, 240-3. [PubMed] [Google Scholar]

32. Adhya S, Black L, Friedman D, Hatfull G, Kreuzer K, Merril C, Oppenheim A, Rohwer F, Young R. 2004 ASM Conference on the New Phage Biology: the 'Phage Summit'. Mol Microbiol. 2005;55:1300–14. doi: 10.1111/j.1365-2958.2005.04509.x. [PubMed] [CrossRef] [Google Scholar]

33. Ackerman HW. Obituary – Hansjürgen Raettig – Collector of bacteriophages references. BEG news.2000; 3:5 (http://phage.org/2000)

34. Ackermann HW. Who went into phage research? Bacteriophage. 2012;2:55–9. doi: 10.4161/bact.18680.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

35. Ackermann HW, Prangishvili D. Prokaryote viruses studied by electron microscopy. Arch Virol. 2012;157:1843–9. doi: 10.1007/s00705-012-1383-y. [PubMed] [CrossRef] [Google Scholar]

36. Deghorain M, Van Melderen L. The Staphylococci phages family: an overview. Viruses. 2012;4:3316–35. doi: 10.3390/v4123316.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

37. Ceyssens PJ, Lavigne R. Bacteriophages of Pseudomonas. Future Microbiol. 2010;5:1041–55. doi: 10.2217/fmb.10.66. [PubMed] [CrossRef] [Google Scholar]

38. Ackermann HW. [Bacteriophages: characteristics and 1st stages of a classification] Pathol Biol (Paris) 1969;17:1003–24. [PubMed] [Google Scholar]

39. Ackermann HW. Bacteriophage taxonomy in 1987. Microbiol Sci. 1987;4:214–8. [PubMed] [Google Scholar]

40. Ackermann HW. Frequency of morphological phage descriptions in 1995. Arch Virol. 1996;141:209–18. doi: 10.1007/BF01718394. [PubMed] [CrossRef] [Google Scholar]

41. Rohwer F, Edwards R. The Phage Proteomic Tree: a genome-based taxonomy for phage. J Bacteriol. 2002;184:4529–35. doi: 10.1128/JB.184.16.4529-4535.2002.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

42. Fauquet CM, Pringle CR. Abbreviations for bacterial and fungal virus species names. Arch Virol. 2000;145:197–203. doi: 10.1007/s007050050017. [PubMed] [CrossRef] [Google Scholar]

43. Drulis-Kawa Z, Majkowska-Skrobek G, Maciejewska B, Delattre AS, Lavigne R. Learning from bacteriophages - advantages and limitations of phage and phage-encoded protein applications. Curr Protein Pept Sci. 2012;13:699–722. doi: 10.2174/138920312804871193.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

44. Chatterjee S, Rothenberg E. Interaction of bacteriophage l with its E. coli receptor, LamB. Viruses. 2012;4:3162–78. doi: 10.3390/v4113162.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

45. Canchaya C, Fournous G, Chibani-Chennoufi S, Dillmann ML, Brüssow H. Phage as agents of lateral gene transfer. Curr Opin Microbiol. 2003;6:417–24. doi: 10.1016/S1369-5274(03)00086-9. [PubMed] [CrossRef] [Google Scholar]

46. Lu TK, Collins JJ. Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy. Proc Natl Acad Sci U S A. 2009;106:4629–34. doi: 10.1073/pnas.0800442106.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

47. Edgar R, Friedman N, Molshanski-Mor S, Qimron U. Reversing bacterial resistance to antibiotics by phage-mediated delivery of dominant sensitive genes. Appl Environ Microbiol. 2012;78:744–51. doi: 10.1128/AEM.05741-11.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

48. Giamarellou H. Multidrug-resistant Gram-negative bacteria: how to treat and for how long. Int J Antimicrob Agents. 2010;36(Suppl 2):S50–4. doi: 10.1016/j.ijantimicag.2010.11.014. [PubMed] [CrossRef] [Google Scholar]

49. Arias CA, Murray BE. Antibiotic-resistant bugs in the 21st century--a clinical super-challenge. N Engl J Med. 2009;360:439–43. doi: 10.1056/NEJMp0804651. [PubMed] [CrossRef] [Google Scholar]

50. Klevens RM, Morrison MA, Nadle J, Petit S, Gershman K, Ray S, Harrison LH, Lynfield R, Dumyati G, Townes JM, et al. Active Bacterial Core surveillance (ABCs) MRSA Investigators Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA. 2007;298:1763–71. doi: 10.1001/jama.298.15.1763. [PubMed] [CrossRef] [Google Scholar]

51. Pendleton JN, Gorman SP, Gilmore BF. Clinical relevance of the ESKAPE pathogens. Expert Rev Anti Infect Ther. 2013;11:297–308. doi: 10.1586/eri.13.12. [PubMed] [CrossRef] [Google Scholar]

52. Morales E, Cots F, Sala M, Comas M, Belvis F, Riu M, Salvadó M, Grau S, Horcajada JP, Montero MM, et al. Hospital costs of nosocomial multi-drug resistant Pseudomonas aeruginosa acquisition. BMC Health Serv Res. 2012;12:122. doi: 10.1186/1472-6963-12-122.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

53. Selgelid MJ. Ethics and drug resistance. Bioethics. 2007;21:218–29. doi: 10.1111/j.1467-8519.2006.00542.x. [PubMed] [CrossRef] [Google Scholar]

54. Aiello AE, King NB, Foxman B. Ethical conflicts in public health research and practice: antimicrobial resistance and the ethics of drug development. Am J Public Health. 2006;96:1910–4. doi: 10.2105/AJPH.2005.077214.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

55. Gravitz L. Turning a new phage. Nat Med. 2012;18:1318–20. doi: 10.1038/nm0912-1318. [PubMed] [CrossRef] [Google Scholar]

56. World Medical Association Statement on Resistance to antimicrobial agents www.wma.net/e/policy/a19htm

57. Freire-Moran L, Aronsson B, Manz C, Gyssens IC, So AD, Monnet DL, Cars O, ECDC-EMA Working Group Critical shortage of new antibiotics in development against multidrug-resistant bacteria-Time to react is now. Drug Resist Updat. 2011;14:118–24. doi: 10.1016/j.drup.2011.02.003. [PubMed] [CrossRef] [Google Scholar]

58. Jabes D. The antibiotic R&D pipeline: an update. Curr Opin Microbiol. 2011;14:564–9. doi: 10.1016/j.mib.2011.08.002. [PubMed] [CrossRef] [Google Scholar]

59. Mahony J, McAuliffe O, Ross RP, van Sinderen D. Bacteriophages as biocontrol agents of food pathogens. Curr Opin Biotechnol. 2011;22:157–63. doi: 10.1016/j.copbio.2010.10.008. [PubMed] [CrossRef] [Google Scholar]

60. Haq IU, Chaudhry WN, Akhtar MN, Andleeb S, Qadri I. Bacteriophages and their implications on future biotechnology: a review. Virol J. 2012;9:9. doi: 10.1186/1743-422X-9-9.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

61. Atterbury RJ. Bacteriophage biocontrol in animals and meat products. Microb Biotechnol. 2009;2:601–12. doi: 10.1111/j.1751-7915.2009.00089.x.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

62. Jain P, Hartman TE, Eisenberg N, O’Donnell MR, Kriakov J, Govender K, Makume M, Thaler DS, Hatfull GF, Sturm AW, et al. φ(2)GFP10, a high-intensity fluorophage, enables detection and rapid drug susceptibility testing of Mycobacterium tuberculosis directly from sputum samples. J Clin Microbiol. 2012;50:1362–9. doi: 10.1128/JCM.06192-11.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

63. Matsuzaki S, Yasuda M, Nishikawa H, Kuroda M, Ujihara T, Shuin T, Shen Y, Jin Z, Fujimoto S, Nasimuzzaman MD, et al. Experimental protection of mice against lethal Staphylococcus aureus infection by novel bacteriophage phi MR11. J Infect Dis. 2003;187:613–24. doi: 10.1086/374001. [PubMed] [CrossRef] [Google Scholar]

64. Biswas B, Adhya S, Washart P, Paul B, Trostel AN, Powell B, Carlton R, Merril CR. Bacteriophage therapy rescues mice bacteremic from a clinical isolate of vancomycin-resistant Enterococcus faecium.Infect Immun. 2002;70:204–10. doi: 10.1128/IAI.70.1.204-210.2002.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

65. Vinodkumar CS, Neelagund YF, Kalsurmath S. Bacteriophage in the treatment of experimental septicemic mice from a clinical isolate of multidrug resistant Klebsiella pneumoniae.J Commun Dis. 2005;37:18–29. [PubMed] [Google Scholar]

66. Wang J, Hu B, Xu M, Yan Q, Liu S, Zhu X, Sun Z, Reed E, Ding L, Gong J, et al. Use of bacteriophage in the treatment of experimental animal bacteremia from imipenem-resistant Pseudomonas aeruginosa.Int J Mol Med. 2006;17:309–17. [PubMed] [Google Scholar]

67. Wang J, Hu B, Xu M, Yan Q, Liu S, Zhu X, Sun Z, Tao D, Ding L, Reed E, et al. Therapeutic effectiveness of bacteriophages in the rescue of mice with extended spectrum β-lactamase-producing Escherichia coli bacteremia. Int J Mol Med. 2006;17:347–55. [PubMed] [Google Scholar]

68. Chibani-Chennoufi S, Sidoti J, Bruttin A, Kutter E, Sarker S, Brüssow H. In vitro and in vivo bacteriolytic activities of Escherichia coli phages: implications for phage therapy. Antimicrob Agents Chemother. 2004;48:2558–69. doi: 10.1128/AAC.48.7.2558-2569.2004.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

69. Bruttin A, Brüssow H. Human volunteers receiving Escherichia coli phage T4 orally: a safety test of phage therapy. Antimicrob Agents Chemother. 2005;49:2874–8. doi: 10.1128/AAC.49.7.2874-2878.2005.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

70. Sarker SA, McCallin S, Barretto C, Berger B, Pittet AC, Sultana S, Krause L, Huq S, Bibiloni R, Bruttin A, et al. Oral T4-like phage cocktail application to healthy adult volunteers from Bangladesh. Virology. 2012;434:222–32. doi: 10.1016/j.virol.2012.09.002. [PubMed] [CrossRef] [Google Scholar]

71. Pouillot F, Chomton M, Blois H, Courroux C, Noelig J, Bidet P, Bingen E, Bonacorsi S. Efficacy of bacteriophage therapy in experimental sepsis and meningitis caused by a clone O25b:H4-ST131 Escherichia coli strain producing CTX-M-15. Antimicrob Agents Chemother. 2012;56:3568–75. doi: 10.1128/AAC.06330-11.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

72. Alisky J, Iczkowski K, Rapoport A, Troitsky N. Bacteriophages show promise as antimicrobial agents. J Infect. 1998;36:5–15. doi: 10.1016/S0163-4453(98)92874-2. [PubMed] [CrossRef] [Google Scholar]

73. Górski A, Miedzybrodzki R, Borysowski J, Weber-Dabrowska B, Lobocka M, Fortuna W, Letkiewicz S, Zimecki M, Filby G. Bacteriophage therapy for the treatment of infections. Curr Opin Investig Drugs. 2009;10:766–74. [PubMed] [Google Scholar]

74. Azeredo J, Sutherland IW. The use of phages for the removal of infectious biofilms. Curr Pharm Biotechnol. 2008;9:261–6. doi: 10.2174/138920108785161604. [PubMed] [CrossRef] [Google Scholar]

75. Weber-Dabrowska B, Zimecki M, Mulczyk M. Effective phage therapy is associated with normalization of cytokine production by blood cell cultures. Arch Immunol Ther Exp (Warsz) 2000;48:31–7. [PubMed] [Google Scholar]

76. Miedzybrodzki R, Fortuna W, Weber-Dabrowska B, Górski A. A retrospective analysis of changes in inflammatory markers in patients treated with bacterial viruses. Clin Exp Med. 2009;9:303–12. doi: 10.1007/s10238-009-0044-2. [PubMed] [CrossRef] [Google Scholar]

77. Międzybrodzki R, Borysowski J, Weber-Dąbrowska B, Fortuna W, Letkiewicz S, Szufnarowski K, Pawełczyk Z, Rogóż P, Kłak M, Wojtasik E, et al. Clinical aspects of phage therapy. Adv Virus Res. 2012;83:73–121. doi: 10.1016/B978-0-12-394438-2.00003-7. [PubMed] [CrossRef] [Google Scholar]

78. Weber-Dabrowska B, Zimecki M, Mulczyk M, Górski A. Effect of phage therapy on the turnover and function of peripheral neutrophils. FEMS Immunol Med Microbiol. 2002;34:135–8. doi: 10.1111/j.1574-695X.2002.tb00614.x. [PubMed] [CrossRef] [Google Scholar]

79. Górski A, Międzybrodzki R, Borysowski J, Dąbrowska K, Wierzbicki P, Ohams M, Korczak-Kowalska G, Olszowska-Zaremba N, Łusiak-Szelachowska M, Kłak M, et al. Phage as a modulator of immune responses: practical implications for phage therapy. Adv Virus Res. 2012;83:41–71. doi: 10.1016/B978-0-12-394438-2.00002-5. [PubMed] [CrossRef] [Google Scholar]

80. Miedzybrodzki R, Fortuna W, Weber-Dabrowska B, Górski A. Phage therapy of staphylococcal infections (including MRSA) may be less expensive than antibiotic treatment. Postepy Hig Med Dosw (Online) 2007;61:461–5. [PubMed] [Google Scholar]

81. Merabishvili M, De Vos D, Verbeken G, Kropinski AM, Vandenheuvel D, Lavigne R, Wattiau P, Mast J, Ragimbeau C, Mossong J, et al. Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli O104:H4 strain from the 2011 outbreak in Germany. PLoS One. 2012;7:e52709. doi: 10.1371/journal.pone.0052709.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

82. Merabishvili M, Pirnay JP, Verbeken G, Chanishvili N, Tediashvili M, Lashkhi N, Glonti T, Krylov V, Mast J, Van Parys L, et al. Quality-controlled small-scale production of a well-defined bacteriophage cocktail for use in human clinical trials. PLoS One. 2009;4:e4944. doi: 10.1371/journal.pone.0004944.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

83. Pirnay JP, De Vos D, Verbeken G, Merabishvili M, Chanishvili N, Vaneechoutte M, Zizi M, Laire G, Lavigne R, Huys I, et al. The phage therapy paradigm: prêt-à-porter or sur-mesure? Pharm Res. 2011;28:934–7. doi: 10.1007/s11095-010-0313-5. [PubMed] [CrossRef] [Google Scholar]

84. Jończyk E, Kłak M, Międzybrodzki R, Górski A. The influence of external factors on bacteriophages--review. Folia Microbiol (Praha) 2011;56:191–200. doi: 10.1007/s12223-011-0039-8.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

85. Brabban AD, Hite E, Callaway TR. Evolution of foodborne pathogens via temperate bacteriophage-mediated gene transfer. Foodborne Pathog Dis. 2005;2:287–303. doi: 10.1089/fpd.2005.2.287. [PubMed] [CrossRef] [Google Scholar]

86. O’Shea YA, Boyd EF. Mobilization of the Vibrio pathogenicity island between Vibrio cholerae isolates mediated by CP-T1 generalized transduction. FEMS Microbiol Lett. 2002;214:153–7. doi: 10.1111/j.1574-6968.2002.tb11339.x. [PubMed] [CrossRef] [Google Scholar]

87. Maiques E, Ubeda C, Tormo MA, Ferrer MD, Lasa I, Novick RP, Penadés JR. Role of staphylococcal phage and SaPI integrase in intra- and interspecies SaPI transfer. J Bacteriol. 2007;189:5608–16. doi: 10.1128/JB.00619-07.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

88. Hatfull GF. Bacteriophage genomics. Curr Opin Microbiol. 2008;11:447–53. doi: 10.1016/j.mib.2008.09.004.[PMC free article] [PubMed] [CrossRef] [Google Scholar]

89. Ackermann HW, Kropinski AM. Curated list of prokaryote viruses with fully sequenced genomes. Res Microbiol. 2007;158:555–66. doi: 10.1016/j.resmic.2007.07.006. [PubMed] [CrossRef] [Google Scholar]

90. Goodridge LD. Designing phage therapeutics. Curr Pharm Biotechnol. 2010;11:15–27. doi: 10.2174/138920110790725348. [PubMed] [CrossRef] [Google Scholar]

91. Dabrowska K, Switała-Jelen K, Opolski A, Weber-Dabrowska B, Gorski A. Bacteriophage penetration in vertebrates. J Appl Microbiol. 2005;98:7–13. doi: 10.1111/j.1365-2672.2004.02422.x. [PubMed] [CrossRef] [Google Scholar]

92. Liu M, Deora R, Doulatov SR, Gingery M, Eiserling FA, Preston A, Maskell DJ, Simons RW, Cotter PA, Parkhill J, et al. Reverse transcriptase-mediated tropism switching in Bordetella bacteriophage. Science. 2002;295:2091–4. doi: 10.1126/science.1067467. [PubMed

Sours: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916379/

Similar news:

Opal V. Anderson McMillion Chapman, 98 years, 7 months, went home to be with the Lord on Monday, August 31, 2020 at Braxton Health Care Center. She was born February 02, 1922 in Removal to the late Earl and Rebecca Cogar Anderson, the youngest of eleven children, and the last surviving, and was a lifelong resident of Webster County. Opal was a member of Word of Life Fellowship Church. She was very active in her church, singing and playing the guitar. She also sang at numerous funerals throughout the county. She enjoyed writing short stories and loved spending time with her family, especially spoiling her grandchildren. She is survived by her son Dwight McMillion (Sharon) of South Pointe, OH; daughters Sheila McCourt (Arnold Doyle) of Wellington, OH and Betty McMillion (John) of Craigsville; eight grandchildren; 10 great-grandchildren; step-daughters Rose Mary Chapman and Marlene Szuch, both of Seville, OH; and many other extended family and friends who will mourn her passing. In addition to her parents she was preceded in death by her first husband of 30 years, Maynard McMillion; second husband of 31 years, Denzil Chapman; seven brothers; and three sisters. The family wishes to extend special thanks to the Staff of Braxton Health Care Center for the care that was shown to Opal. A very special thank you to Jeannie Stout and Linda Morrison; their care and concern allowed Opal and Denzil to stay independently in their home for an extended time. Friends may join the family for Celebration of Life Services on Saturday, September 05, 2020 at 2:00 PM at Dodd & Reed Funeral Home with Pastor Eddie Bender officiating. Interment will follow in Alexander Anderson Cemetery, Hacker Valley. Online condolences may be made to the family at www.doddreedfh.com. Dodd & Reed Funeral Home is honored to be serving the McMillion/Chapman family. Due to the COVID-19 Virus, all who attend the services please practice the social distancing guidelines set forth by the CDC and the state of WV, including wearing of facial coverings.

BRIDGEPORT, W.Va (WDTV) -

Copyright 2020 WDTV. All rights reserved.

Sours: https://www.wdtv.com/2020/09/01/opal-v-anderson-mcmillion-chapman/


1340 1341 1342 1343 1344